{"id":332353,"date":"2020-12-06T13:00:00","date_gmt":"2020-12-06T12:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/erenumab-effective-and-safe-in-the-long-term-in-clinical-practice\/"},"modified":"2020-12-06T13:00:00","modified_gmt":"2020-12-06T12:00:00","slug":"erenumab-effective-and-safe-in-the-long-term-in-clinical-practice","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/erenumab-effective-and-safe-in-the-long-term-in-clinical-practice\/","title":{"rendered":"Erenumab effective and safe in the long term in clinical practice"},"content":{"rendered":"<p><strong>Recent trial data strengthen the role of erenumab as a preventive migraine treatment. They confirm the real and long-term benefits of the CGRP inhibitor in terms of safety and efficacy in patients with episodic and chronic migraine.  <\/strong><\/p>\n<p> <!--more--> <\/p>\n<p>Migraine is a highly disabling disease that has a profound and limiting impact on people&#8217;s lives &#8211; including the time they spend with family and friends or at work. Erenumab (<sup>Aimovig\u00ae<\/sup>) is the first and only FDA-approved migraine prevention treatment that targets the calcitonin gene-related peptide (CGRP) receptor. It is self-administered once a month via the <sup>SureClick\u00ae<\/sup> auto-injector, requires no starting dose, and is easy to use. Interim results from the TELESCOPE study, conducted in 109 patients in Germany, showed that 80% of erenumab patients reported a reduction in migraine intensity. 92% of sufferers also had fewer attacks, with an average reduction of 8 migraine days per month (MMD). In addition, interim results from the PERISCOPE study showed that 85% of patients taking <sup>Aimovig\u00ae<\/sup> were able to better manage daily activities. In fact, 83% lost fewer days due to migraines since starting treatment.<\/p>\n<h2 id=\"long-term-reduction-of-mmd\">Long-term reduction of MMD<\/h2>\n<p>Results from a 4.5-year interim analysis of the open-label phase II clinical trial in patients with episodic migraine showed that long-term treatment with erenumab resulted in a sustained reduction in MMD. Patients with episodic migraine who switched from 70&nbsp;mg to 140&nbsp;mg and remained at 140&nbsp;mg after \u22654 years had an average of 5.8 fewer MMD compared with the study baseline (8.7 MMD). In a subanalysis of patients with chronic migraine and acute medication overuse (AMO), long-term treatment reduced MMD by 8.9 days and 10 days, respectively, and by 8.2 and 10.8 days in non-AMO patients. These results support the use of <sup>Aimovig\u00ae<\/sup> for migraine prevention across the migraine spectrum.<\/p>\n<p>\n<em>InFo NEUROLOGY &amp; PSYCHIATRY 2020; 18(5): 39.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recent trial data strengthen the role of erenumab as a preventive migraine treatment. They confirm the real and long-term benefits of the CGRP inhibitor in terms of safety and efficacy&hellip;<\/p>\n","protected":false},"author":7,"featured_media":99300,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Migraine prevention  ","footnotes":""},"category":[11530,11363,11548,11503],"tags":[22948,13856,16084],"powerkit_post_featured":[],"class_list":["post-332353","post","type-post","status-publish","format-standard","has-post-thumbnail","category-market-medicine","category-neurology","category-rx-en","category-studies","tag-cgrp-inhibitor-en","tag-migraine","tag-migraine-prophylaxis","pmpro-has-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-13 17:25:50","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":332293,"slug":"erenumab-efficace-et-sur-a-long-terme-en-pratique-clinique-quotidienne","post_title":"Erenumab efficace et s\u00fbr \u00e0 long terme en pratique clinique quotidienne","href":"https:\/\/medizinonline.com\/fr\/erenumab-efficace-et-sur-a-long-terme-en-pratique-clinique-quotidienne\/"},"it_IT":{"locale":"it_IT","id":332486,"slug":"erenumab-efficace-e-sicuro-nella-pratica-clinica-a-lungo-termine","post_title":"Erenumab efficace e sicuro nella pratica clinica a lungo termine","href":"https:\/\/medizinonline.com\/it\/erenumab-efficace-e-sicuro-nella-pratica-clinica-a-lungo-termine\/"},"pt_PT":{"locale":"pt_PT","id":332357,"slug":"erenumab-eficaz-e-seguro-na-pratica-clinica-a-longo-prazo","post_title":"Erenumab eficaz e seguro na pr\u00e1tica cl\u00ednica a longo prazo","href":"https:\/\/medizinonline.com\/pt-pt\/erenumab-eficaz-e-seguro-na-pratica-clinica-a-longo-prazo\/"},"es_ES":{"locale":"es_ES","id":332317,"slug":"erenumab-eficaz-y-seguro-en-la-practica-clinica-a-largo-plazo","post_title":"Erenumab eficaz y seguro en la pr\u00e1ctica cl\u00ednica a largo plazo","href":"https:\/\/medizinonline.com\/es\/erenumab-eficaz-y-seguro-en-la-practica-clinica-a-largo-plazo\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/332353","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=332353"}],"version-history":[{"count":0,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/332353\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/99300"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=332353"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=332353"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=332353"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=332353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}