{"id":335012,"date":"2020-01-10T00:00:00","date_gmt":"2020-01-09T23:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/study-suggests-anti-atherosclerotic-effect-from-omega-3-fatty-acids\/"},"modified":"2020-01-10T00:00:00","modified_gmt":"2020-01-09T23:00:00","slug":"study-suggests-anti-atherosclerotic-effect-from-omega-3-fatty-acids","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/study-suggests-anti-atherosclerotic-effect-from-omega-3-fatty-acids\/","title":{"rendered":"Study suggests anti-atherosclerotic effect from omega-3 fatty acids"},"content":{"rendered":"<p><strong>&#8220;Fish oil&#8221; as a heart protector is always controversially discussed &#8211; and just as contradictorily tested. Some studies can demonstrate a protective effect, many others cannot. Now, for the first time, evidence of delayed progression of atherosclerosis has been demonstrated under a specific preparation.<\/strong><\/p>\n<p> <!--more--> <\/p>\n<p>Back in 2018, results of a study were presented that demonstrated for the first time a protective effect against cardiovascular events by substituting marine omea-3 fatty acids. 8179 patients with elevated triglyceride levels (&gt;150 to &lt;500 mg\/dl) and quite low LDL cholesterol levels (41 to 100 mg\/dl) received a high dose of eicosapentaenoic acid (EPA) in pure form (icosapent-ethyl). All patients were taking statins and many already had cardiovascular disease or diabetes in combination with at least one other risk factor. High-dose EPA intake was shown to produce a significant 25% risk reduction in the primary composite end point (cardiovascular-related death, nonfatal myocardial infarction or stroke, hospitalization for unstable angina, or coronary revascularization).<\/p>\n<p>A follow-up study is now investigating how this protective effect comes about. In 80 patients, the development of coronary atherosclerosis will be studied under the drug compared to placebo. A multislice CT measurement will be performed at baseline, nine months, and 18 months to detect any changes in coronary plaque morphology.<\/p>\n<h2 id=\"stop-atherosclerosis\">Stop atherosclerosis<\/h2>\n<p>An interim analysis of the initial data at nine months shows early evidence of delayed progression of atherosclerosis by 21% with icosapent-ethyl. This difference is currently not yet significant. In contrast, other plaque morphologies such as calcified, non-calcified or fibrous lesions and total plaque volume already showed significant differences in favor of the &#8220;fish oil&#8221;. The final results after completion of the 18-month study period are eagerly awaited.<\/p>\n<p><em>Source: American Heart Association (AHA)<\/em><br \/>\n&nbsp;<\/p>\n<p><em>CARDIOVASC 2019; 18(6): 36 (published 5\/12\/19, ahead of print).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Fish oil&#8221; as a heart protector is always controversially discussed &#8211; and just as contradictorily tested. Some studies can demonstrate a protective effect, many others cannot. Now, for the first&hellip;<\/p>\n","protected":false},"author":7,"featured_media":93140,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Cardiovascular events","footnotes":""},"category":[11359,11513,11388,11460,11548,11503],"tags":[26604,12123,26606,26612,26610,26608],"powerkit_post_featured":[],"class_list":["post-335012","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cardiology","category-congress-reports","category-nutrition","category-prevention-and-health-care","category-rx-en","category-studies","tag-aha-en","tag-atherosclerosis","tag-cardiovascular-events","tag-fish-oil","tag-omega-3-en","tag-omega-3-fatty-acids","pmpro-has-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-06 10:05:17","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":335018,"slug":"une-etude-suggere-un-effet-anti-atherosclerotique-des-acides-gras-omega-3","post_title":"Une \u00e9tude sugg\u00e8re un effet anti-ath\u00e9roscl\u00e9rotique des acides gras om\u00e9ga-3","href":"https:\/\/medizinonline.com\/fr\/une-etude-suggere-un-effet-anti-atherosclerotique-des-acides-gras-omega-3\/"},"it_IT":{"locale":"it_IT","id":335021,"slug":"lo-studio-suggerisce-leffetto-anti-aterosclerotico-degli-acidi-grassi-omega-3","post_title":"Lo studio suggerisce l'effetto anti-aterosclerotico degli acidi grassi omega-3","href":"https:\/\/medizinonline.com\/it\/lo-studio-suggerisce-leffetto-anti-aterosclerotico-degli-acidi-grassi-omega-3\/"},"pt_PT":{"locale":"pt_PT","id":335023,"slug":"estudo-sugere-efeito-anti-aterosclerotico-dos-acidos-gordos-omega-3","post_title":"Estudo sugere efeito anti-ateroscler\u00f3tico dos \u00e1cidos gordos \u00f3mega-3","href":"https:\/\/medizinonline.com\/pt-pt\/estudo-sugere-efeito-anti-aterosclerotico-dos-acidos-gordos-omega-3\/"},"es_ES":{"locale":"es_ES","id":335025,"slug":"un-estudio-sugiere-el-efecto-antiaterosclerotico-de-los-acidos-grasos-omega-3","post_title":"Un estudio sugiere el efecto antiateroscler\u00f3tico de los \u00e1cidos grasos omega-3","href":"https:\/\/medizinonline.com\/es\/un-estudio-sugiere-el-efecto-antiaterosclerotico-de-los-acidos-grasos-omega-3\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/335012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=335012"}],"version-history":[{"count":0,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/335012\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/93140"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=335012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=335012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=335012"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=335012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}