{"id":335792,"date":"2019-08-21T02:00:00","date_gmt":"2019-08-21T00:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/nsaids-as-mediators-of-cardiovascular-disease\/"},"modified":"2019-08-21T02:00:00","modified_gmt":"2019-08-21T00:00:00","slug":"nsaids-as-mediators-of-cardiovascular-disease","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/nsaids-as-mediators-of-cardiovascular-disease\/","title":{"rendered":"NSAIDs as mediators of cardiovascular disease?"},"content":{"rendered":"<p><strong>Osteoarthritis is usually treated effectively with NSAIDs. Pain and inflammatory processes can thus be contained. But does the treatment entail cardiovascular risk?<\/strong><\/p>\n<p> <!--more--> <\/p>\n<p>The population-based longitudinal study, recently published in Arthritis &amp; Rheumatology, is based on health data from British Columbia, Canada. From a cohort of over 720,000 individuals, 7743 osteoarthritis patients were matched with 23,229 non-arthritis controls. The study authors found that the risk of developing cardiovascular disease was 23% higher among osteoarthritis patients compared with controls without osteoarthritis. Secondary endpoints focused on risk of heart failure (42% higher in osteoarthritis patients), ischemic heart disease (17% higher), and stroke (14% higher). Among these, approximately 41% of the increased risk of developing cardiovascular disease as an osteoarthritis patient was mediated by the use of NSAIDs.<\/p>\n<p>Study leader Aslam Anis of the UBC School of Population and Public Health sums up, &#8220;Our results indicate that osteoarthritis is an independent risk factor for the development of cardiovascular disease, and they suggest that NSAID use contributes substantially to this increased risk.&#8221; Given the widespread use of NSAIDs, these results are highly relevant. Aslam Anis therefore stresses the importance of educating osteoarthritis patients about the benefits, but also the risks, of NSAIDs.<\/p>\n<p><em>Source: Atiquzzaman M, et al: Role of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in the Association between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study. Arthritis Rheumatol. 2019 Aug 6. doi: 10.1002\/art.41027 [Epub ahead of print].<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><em>HAUSARZT PRAXIS 2019; 14(8): 4 (published 8\/21\/19, ahead of print).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Osteoarthritis is usually treated effectively with NSAIDs. Pain and inflammatory processes can thus be contained. But does the treatment entail cardiovascular risk?<\/p>\n","protected":false},"author":7,"featured_media":90576,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Osteoarthritis and cardiovascular risk","footnotes":""},"category":[11359,11297,11500,11480,11548,11503],"tags":[17537,21603],"powerkit_post_featured":[],"class_list":["post-335792","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cardiology","category-general-internal-medicine","category-news-en","category-rheumatology","category-rx-en","category-studies","tag-nsaid-en","tag-osteoarthritis-en","pmpro-has-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-07 14:52:29","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":335798,"slug":"les-ains-mediateurs-des-maladies-cardiovasculaires","post_title":"Les AINS, m\u00e9diateurs des maladies cardiovasculaires ?","href":"https:\/\/medizinonline.com\/fr\/les-ains-mediateurs-des-maladies-cardiovasculaires\/"},"it_IT":{"locale":"it_IT","id":335803,"slug":"i-fans-come-mediatori-della-malattia-cardiovascolare","post_title":"I FANS come mediatori della malattia cardiovascolare?","href":"https:\/\/medizinonline.com\/it\/i-fans-come-mediatori-della-malattia-cardiovascolare\/"},"pt_PT":{"locale":"pt_PT","id":335812,"slug":"os-ains-como-mediadores-das-doencas-cardiovasculares","post_title":"Os AINS como mediadores das doen\u00e7as cardiovasculares?","href":"https:\/\/medizinonline.com\/pt-pt\/os-ains-como-mediadores-das-doencas-cardiovasculares\/"},"es_ES":{"locale":"es_ES","id":335780,"slug":"los-aine-como-mediadores-de-las-enfermedades-cardiovasculares","post_title":"\u00bfLos AINE como mediadores de las enfermedades cardiovasculares?","href":"https:\/\/medizinonline.com\/es\/los-aine-como-mediadores-de-las-enfermedades-cardiovasculares\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/335792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=335792"}],"version-history":[{"count":0,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/335792\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/90576"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=335792"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=335792"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=335792"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=335792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}