{"id":393536,"date":"2025-02-13T00:01:00","date_gmt":"2025-02-12T23:01:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=393536"},"modified":"2025-02-12T22:04:05","modified_gmt":"2025-02-12T21:04:05","slug":"wolfram-syndrome","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/wolfram-syndrome\/","title":{"rendered":"Wolfram syndrome"},"content":{"rendered":"\n<p><strong>The term &#8220;DIDMOAD&#8221; syndrome &#8211; an acronym for the characteristic symptoms &#8211; serves as an alternative name for this autosomal recessive neurodegenerative disease, which was first described in 1938: Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness\/Deafness. In the majority of patients, mutations in the WFS1 gene can be detected. <\/strong><\/p>\n\n\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwolfram-syndrome%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The term &#8220;DIDMOAD&#8221; syndrome &#8211; an acronym for the characteristic symptoms &#8211; serves as an alternative name for this autosomal recessive neurodegenerative disease, which was first described in 1938: Diabetes&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwolfram-syndrome%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":393543,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Rare diseases","footnotes":""},"category":[11548,11359,11508,11384,11297,11396,11413,11363,11427,11466,11503,11490],"tags":[11655,80738,13137,26450,80742,80740],"powerkit_post_featured":[],"class_list":["post-393536","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-cardiology","category-education","category-endocrinology-and-diabetology","category-general-internal-medicine","category-genetics","category-nephrology","category-neurology","category-orl-en","category-psychiatry-and-psychotherapy","category-studies","category-urology","tag-diabetes-en","tag-didmoad-en","tag-mutations","tag-rare-diseases-en","tag-wfs1-en","tag-wolfram-syndrome","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-10 09:35:40","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":393555,"slug":"syndrome-de-wolfram","post_title":"Syndrome de Wolfram","href":"https:\/\/medizinonline.com\/fr\/syndrome-de-wolfram\/"},"it_IT":{"locale":"it_IT","id":393538,"slug":"sindrome-di-wolfram","post_title":"Sindrome di Wolfram","href":"https:\/\/medizinonline.com\/it\/sindrome-di-wolfram\/"},"pt_PT":{"locale":"pt_PT","id":393535,"slug":"sindrome-de-wolfram","post_title":"S\u00edndrome de Wolfram","href":"https:\/\/medizinonline.com\/pt-pt\/sindrome-de-wolfram\/"},"es_ES":{"locale":"es_ES","id":393528,"slug":"sindrome-de-wolfram","post_title":"S\u00edndrome de Wolfram","href":"https:\/\/medizinonline.com\/es\/sindrome-de-wolfram\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/393536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=393536"}],"version-history":[{"count":3,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/393536\/revisions"}],"predecessor-version":[{"id":394891,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/393536\/revisions\/394891"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/393543"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=393536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=393536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=393536"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=393536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}