{"id":396760,"date":"2025-04-24T01:05:00","date_gmt":"2025-04-23T23:05:00","guid":{"rendered":"https:\/\/medizinonline.com\/next-generation-serd-therapy-with-promising-results\/"},"modified":"2025-04-23T23:04:56","modified_gmt":"2025-04-23T21:04:56","slug":"next-generation-serd-therapy-with-promising-results","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/next-generation-serd-therapy-with-promising-results\/","title":{"rendered":"Next-generation SERD therapy with promising results"},"content":{"rendered":"\n<p><strong>The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast cancer (ABC), were presented at the SABCS. The study shows that patients with an ESR1 mutation in particular benefit. <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fnext-generation-serd-therapy-with-promising-results%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fnext-generation-serd-therapy-with-promising-results%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":396761,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Advanced breast cancer","footnotes":""},"category":[11548,11513,11400,11370,11503],"tags":[13554,81832,81833,16456,81809,81831],"powerkit_post_featured":[],"class_list":["post-396760","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-congress-reports","category-gynecology","category-oncology","category-studies","tag-breast-cancer-en","tag-esr1-mutation-en","tag-imlunestrant-en","tag-sabcs-en","tag-sabcs-2024-en","tag-serd-therapy","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-17 15:58:04","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":396753,"slug":"traitement-serd-de-nouvelle-generation-avec-des-resultats-prometteurs","post_title":"Traitement SERD de nouvelle g\u00e9n\u00e9ration avec des r\u00e9sultats prometteurs","href":"https:\/\/medizinonline.com\/fr\/traitement-serd-de-nouvelle-generation-avec-des-resultats-prometteurs\/"},"it_IT":{"locale":"it_IT","id":396746,"slug":"terapia-serd-di-nuova-generazione-con-risultati-promettenti","post_title":"Terapia SERD di nuova generazione con risultati promettenti","href":"https:\/\/medizinonline.com\/it\/terapia-serd-di-nuova-generazione-con-risultati-promettenti\/"},"pt_PT":{"locale":"pt_PT","id":396740,"slug":"terapia-serd-de-nova-geracao-com-resultados-promissores","post_title":"Terapia SERD de nova gera\u00e7\u00e3o com resultados promissores","href":"https:\/\/medizinonline.com\/pt-pt\/terapia-serd-de-nova-geracao-com-resultados-promissores\/"},"es_ES":{"locale":"es_ES","id":396734,"slug":"terapia-serd-de-nueva-generacion-con-resultados-prometedores","post_title":"Terapia SERD de nueva generaci\u00f3n con resultados prometedores","href":"https:\/\/medizinonline.com\/es\/terapia-serd-de-nueva-generacion-con-resultados-prometedores\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/396760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=396760"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/396760\/revisions"}],"predecessor-version":[{"id":396762,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/396760\/revisions\/396762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/396761"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=396760"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=396760"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=396760"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=396760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}