{"id":397852,"date":"2025-05-21T01:05:00","date_gmt":"2025-05-20T23:05:00","guid":{"rendered":"https:\/\/medizinonline.com\/pcsk9-inhibitors-current-evidence-mechanisms-and-unanswered-questions\/"},"modified":"2025-05-21T02:39:13","modified_gmt":"2025-05-21T00:39:13","slug":"pcsk9-inhibitors-current-evidence-mechanisms-and-unanswered-questions","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/pcsk9-inhibitors-current-evidence-mechanisms-and-unanswered-questions\/","title":{"rendered":"PCSK9 inhibitors: Current evidence, mechanisms and unanswered questions"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Venous thromboembolism (VTE), consisting of deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cause of cardiovascular mortality worldwide after myocardial infarction and stroke. Despite continuous progress in anticoagulation, a specific preventive strategy against VTE that goes beyond anticoagulation is still lacking. In recent years, it has been shown that arterial and venous thromboembolism share more common risk factors than previously thought, including dyslipidemia and inflammatory processes.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fpcsk9-inhibitors-current-evidence-mechanisms-and-unanswered-questions%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Venous thromboembolism (VTE), consisting of deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cause of cardiovascular mortality worldwide after myocardial infarction and stroke. Despite continuous&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fpcsk9-inhibitors-current-evidence-mechanisms-and-unanswered-questions%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":397854,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Venous thromboembolism prevention","footnotes":""},"category":[11548,11359,11508,11503],"tags":[18144,33856,20541,20539,18532,27507],"powerkit_post_featured":[],"class_list":["post-397852","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-cardiology","category-education","category-studies","tag-cholesterol","tag-fourier-en","tag-ldl-en","tag-pcsk9-en","tag-thromboembolism-en","tag-thrombosis","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-13 19:49:09","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":397915,"slug":"inhibiteurs-de-pcsk9-preuves-actuelles-mecanismes-et-questions-en-suspens","post_title":"Inhibiteurs de PCSK9 : Preuves actuelles, m\u00e9canismes et questions en suspens","href":"https:\/\/medizinonline.com\/fr\/inhibiteurs-de-pcsk9-preuves-actuelles-mecanismes-et-questions-en-suspens\/"},"it_IT":{"locale":"it_IT","id":397910,"slug":"inibitori-della-pcsk9-evidenze-attuali-meccanismi-e-domande-aperte","post_title":"Inibitori della PCSK9: Evidenze attuali, meccanismi e domande aperte","href":"https:\/\/medizinonline.com\/it\/inibitori-della-pcsk9-evidenze-attuali-meccanismi-e-domande-aperte\/"},"pt_PT":{"locale":"pt_PT","id":397905,"slug":"inibidores-da-pcsk9-evidencias-actuais-mecanismos-e-questoes-em-aberto","post_title":"Inibidores da PCSK9: Evid\u00eancias actuais, mecanismos e quest\u00f5es em aberto","href":"https:\/\/medizinonline.com\/pt-pt\/inibidores-da-pcsk9-evidencias-actuais-mecanismos-e-questoes-em-aberto\/"},"es_ES":{"locale":"es_ES","id":397900,"slug":"inhibidores-de-la-pcsk9-pruebas-actuales-mecanismos-y-cuestiones-abiertas","post_title":"Inhibidores de la PCSK9: Pruebas actuales, mecanismos y cuestiones abiertas","href":"https:\/\/medizinonline.com\/es\/inhibidores-de-la-pcsk9-pruebas-actuales-mecanismos-y-cuestiones-abiertas\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/397852","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=397852"}],"version-history":[{"count":2,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/397852\/revisions"}],"predecessor-version":[{"id":401525,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/397852\/revisions\/401525"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/397854"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=397852"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=397852"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=397852"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=397852"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}