{"id":405472,"date":"2025-08-12T01:05:00","date_gmt":"2025-08-11T23:05:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=405472"},"modified":"2025-08-08T07:50:54","modified_gmt":"2025-08-08T05:50:54","slug":"effects-of-midazolam-and-dexmedetomidine","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/effects-of-midazolam-and-dexmedetomidine\/","title":{"rendered":"Effects of midazolam and dexmedetomidine"},"content":{"rendered":"\n<p><strong>With demographic change and the rising average age of cardiology patients, post-operative cognitive dysfunction (POCD) following heart surgery is becoming increasingly important in clinical terms. If it occurs, patients often suffer from memory loss, concentration problems and slower information processing for months &#8211; symptoms that can significantly impair the rehabilitation outcome and quality of life. In their comprehensive review, Tabari et al [1] summarize the current state of research on two key sedatives: Midazolam, a long-established benzodiazepine, and dexmedetomidine (DEX), a newer, highly selective \u03b12-adrenergic agent that shows promising neuroprotective properties.   <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Feffects-of-midazolam-and-dexmedetomidine%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>With demographic change and the rising average age of cardiology patients, post-operative cognitive dysfunction (POCD) following heart surgery is becoming increasingly important in clinical terms. If it occurs, patients often&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Feffects-of-midazolam-and-dexmedetomidine%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":405477,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Postoperative cognitive dysfunction","footnotes":""},"category":[11548,11375,11359,11508,11442,11503,11380],"tags":[84267,84268,84269],"powerkit_post_featured":[],"class_list":["post-405472","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-anesthesiology","category-cardiology","category-education","category-pharmacology-and-toxicology","category-studies","category-surgery","tag-dexmedetomidine","tag-midazolam-en","tag-pocd-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-12 20:30:28","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":405561,"slug":"effets-du-midazolam-et-de-la-dexmedetomidine","post_title":"Effets du midazolam et de la dexm\u00e9d\u00e9tomidine","href":"https:\/\/medizinonline.com\/fr\/effets-du-midazolam-et-de-la-dexmedetomidine\/"},"it_IT":{"locale":"it_IT","id":405476,"slug":"effetti-di-midazolam-e-dexmedetomidina","post_title":"Effetti di midazolam e dexmedetomidina","href":"https:\/\/medizinonline.com\/it\/effetti-di-midazolam-e-dexmedetomidina\/"},"pt_PT":{"locale":"pt_PT","id":405483,"slug":"efeitos-do-midazolam-e-da-dexmedetomidina","post_title":"Efeitos do midazolam e da dexmedetomidina","href":"https:\/\/medizinonline.com\/pt-pt\/efeitos-do-midazolam-e-da-dexmedetomidina\/"},"es_ES":{"locale":"es_ES","id":405557,"slug":"efectos-del-midazolam-y-la-dexmedetomidina","post_title":"Efectos del midazolam y la dexmedetomidina","href":"https:\/\/medizinonline.com\/es\/efectos-del-midazolam-y-la-dexmedetomidina\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405472","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=405472"}],"version-history":[{"count":2,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405472\/revisions"}],"predecessor-version":[{"id":405893,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405472\/revisions\/405893"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/405477"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=405472"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=405472"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=405472"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=405472"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}