{"id":405528,"date":"2025-07-27T13:30:00","date_gmt":"2025-07-27T11:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=405528"},"modified":"2025-07-26T21:29:57","modified_gmt":"2025-07-26T19:29:57","slug":"ferroptosis-key-mechanisms-and-novel-therapeutic-approaches","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/ferroptosis-key-mechanisms-and-novel-therapeutic-approaches\/","title":{"rendered":"Ferroptosis: key mechanisms and novel therapeutic approaches"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>The global increase in diabetes mellitus is leading to a parallel increase in the incidence of cardiovascular complications, which remain the leading cause of death in this patient group. In recent years, the discovery of ferroptosis, an iron-dependent and non-apoptotic form of programmed cell death, has provided new insights into the pathophysiology of diabetes-associated heart disease. This review article deepens the understanding of the molecular mechanisms underlying ferroptosis in the cardiovascular system in diabetes and highlights innovative pharmacological and experimental therapeutic approaches that target ferroptosis pathways.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fferroptosis-key-mechanisms-and-novel-therapeutic-approaches%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The global increase in diabetes mellitus is leading to a parallel increase in the incidence of cardiovascular complications, which remain the leading cause of death in this patient group. In&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fferroptosis-key-mechanisms-and-novel-therapeutic-approaches%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":405533,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Diabetes-related cardiovascular diseases","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11548,11359,11508,11384,11353,11503],"tags":[12366,84289,84290],"powerkit_post_featured":[],"class_list":["post-405528","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-cardiology","category-education","category-endocrinology-and-diabetology","category-hematology","category-studies","tag-diabetes-mellitus-en","tag-ferroptosis","tag-iron-metabolism","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-26 04:31:17","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":405525,"slug":"ferroptose-mecanismes-cles-et-nouvelles-approches-therapeutiques","post_title":"Ferroptose : m\u00e9canismes cl\u00e9s et nouvelles approches th\u00e9rapeutiques","href":"https:\/\/medizinonline.com\/fr\/ferroptose-mecanismes-cles-et-nouvelles-approches-therapeutiques\/"},"it_IT":{"locale":"it_IT","id":405527,"slug":"ferroptosi-meccanismi-chiave-e-nuovi-approcci-terapeutici","post_title":"Ferroptosi: meccanismi chiave e nuovi approcci terapeutici","href":"https:\/\/medizinonline.com\/it\/ferroptosi-meccanismi-chiave-e-nuovi-approcci-terapeutici\/"},"pt_PT":{"locale":"pt_PT","id":405542,"slug":"ferroptose-mecanismos-chave-e-novas-abordagens-terapeuticas","post_title":"Ferroptose: mecanismos-chave e novas abordagens terap\u00eauticas","href":"https:\/\/medizinonline.com\/pt-pt\/ferroptose-mecanismos-chave-e-novas-abordagens-terapeuticas\/"},"es_ES":{"locale":"es_ES","id":405523,"slug":"ferroptosis-mecanismos-clave-y-nuevos-enfoques-terapeuticos","post_title":"Ferroptosis: mecanismos clave y nuevos enfoques terap\u00e9uticos","href":"https:\/\/medizinonline.com\/es\/ferroptosis-mecanismos-clave-y-nuevos-enfoques-terapeuticos\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405528","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=405528"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405528\/revisions"}],"predecessor-version":[{"id":405534,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/405528\/revisions\/405534"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/405533"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=405528"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=405528"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=405528"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=405528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}