{"id":407433,"date":"2025-09-17T00:30:00","date_gmt":"2025-09-16T22:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/what-has-stayed-the-same-what-has-changed\/"},"modified":"2025-09-17T01:58:15","modified_gmt":"2025-09-16T23:58:15","slug":"what-has-stayed-the-same-what-has-changed","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/what-has-stayed-the-same-what-has-changed\/","title":{"rendered":"What has stayed the same, what has changed?"},"content":{"rendered":"\n<p><strong>Over the past decades, significant progress has been made in understanding the pathogenesis of chronic inducible urticaria (CIndU). Provocation tests continue to play an important role in confirming the diagnosis. For patients who do not achieve disease control despite H1 antihistamines or omalizumab, numerous biologics and small molecules are currently being investigated in clinical trials, most &#8211; but not all &#8211; of which are directed against new therapeutic targets.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhat-has-stayed-the-same-what-has-changed%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Over the past decades, significant progress has been made in understanding the pathogenesis of chronic inducible urticaria (CIndU). Provocation tests continue to play an important role in confirming the diagnosis&#8230;.&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhat-has-stayed-the-same-what-has-changed%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":407436,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Chronic inducible urticaria  ","footnotes":"[{\"id\":\"b9c3d3b5-fc65-4605-a91d-14d9266c8253\",\"content\":\"CRP = C-reactive protein\"},{\"id\":\"749475e2-a17a-4b23-ba1c-d09367280c88\",\"content\":\"Fc = fragment crystallizable receptor\"},{\"id\":\"96df2223-d897-480c-b881-2a5e453a03d3\",\"content\":\"Fc\\u03b5R-1 = receptor that binds allergen-specific IgE with high affinity\"}]"},"category":[11331,11513,11340,11548,11503],"tags":[26744,84806,12391,84807,63720,65690,18030,13392,84804,84805,15545,26999],"powerkit_post_featured":[],"class_list":["post-407433","post","type-post","status-publish","format-standard","has-post-thumbnail","category-allergology-and-clinical-immunology","category-congress-reports","category-dermatology-and-venereology","category-rx-en","category-studies","tag-anakinra-en","tag-barzolimab-en","tag-biologics-en","tag-chronic-inducible-urticaria-en","tag-cindu-en","tag-h1-antihistamines","tag-ligelizumab-en","tag-omalizumab-en","tag-provocation-tests","tag-remibrutinib-en","tag-small-molecules-en","tag-zdft-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-12 11:32:55","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":407468,"slug":"quest-ce-qui-est-reste-le-meme-quest-ce-qui-a-change","post_title":"Qu'est-ce qui est rest\u00e9 le m\u00eame, qu'est-ce qui a chang\u00e9 ?","href":"https:\/\/medizinonline.com\/fr\/quest-ce-qui-est-reste-le-meme-quest-ce-qui-a-change\/"},"it_IT":{"locale":"it_IT","id":407452,"slug":"cosa-e-rimasto-invariato-e-cosa-e-cambiato","post_title":"Cosa \u00e8 rimasto invariato e cosa \u00e8 cambiato?","href":"https:\/\/medizinonline.com\/it\/cosa-e-rimasto-invariato-e-cosa-e-cambiato\/"},"pt_PT":{"locale":"pt_PT","id":407446,"slug":"o-que-e-que-ficou-na-mesma-o-que-e-que-mudou","post_title":"O que \u00e9 que ficou na mesma, o que \u00e9 que mudou?","href":"https:\/\/medizinonline.com\/pt-pt\/o-que-e-que-ficou-na-mesma-o-que-e-que-mudou\/"},"es_ES":{"locale":"es_ES","id":407438,"slug":"que-ha-permanecido-igual-que-ha-cambiado","post_title":"\u00bfQu\u00e9 ha permanecido igual, qu\u00e9 ha cambiado?","href":"https:\/\/medizinonline.com\/es\/que-ha-permanecido-igual-que-ha-cambiado\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=407433"}],"version-history":[{"count":2,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407433\/revisions"}],"predecessor-version":[{"id":408773,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407433\/revisions\/408773"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/407436"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=407433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=407433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=407433"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=407433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}