{"id":407747,"date":"2025-10-20T00:30:00","date_gmt":"2025-10-19T22:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/early-high-efficacy-as-the-key-to-improving-prognosis\/"},"modified":"2025-09-05T17:08:58","modified_gmt":"2025-09-05T15:08:58","slug":"early-high-efficacy-as-the-key-to-improving-prognosis","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/early-high-efficacy-as-the-key-to-improving-prognosis\/","title":{"rendered":"Early high efficacy as the key to improving prognosis"},"content":{"rendered":"\n<p><strong>Pediatric multiple sclerosis (POMS) is a rare but particularly challenging form of the disease. Children and adolescents with MS often experience more relapses, a greater lesion burden on MRI and early-onset cognitive impairment. At the same time, their long-term course is characterized by a delayed but ultimately unstoppable accumulation of disability. For a long time, therapeutic care was limited and restricted to low to moderately effective therapies. In recent years, however, there has been a paradigm shift: <em>highly effective therapies <\/em>(HETs) are increasingly being used in pediatric patients &#8211; with clear benefits for relapse rate, MRI activity and disease progression.      <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fearly-high-efficacy-as-the-key-to-improving-prognosis%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Pediatric multiple sclerosis (POMS) is a rare but particularly challenging form of the disease. Children and adolescents with MS often experience more relapses, a greater lesion burden on MRI and&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fearly-high-efficacy-as-the-key-to-improving-prognosis%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":407751,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Pediatric multiple sclerosis","footnotes":""},"category":[11508,11396,11363,11437,11442,11548,11503],"tags":[13687,84997,12354,35776,84998],"powerkit_post_featured":[],"class_list":["post-407747","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-genetics","category-neurology","category-pediatrics","category-pharmacology-and-toxicology","category-rx-en","category-studies","tag-biomarker-en","tag-highly-effective-therapies","tag-multiple-sclerosis","tag-paradigms-en","tag-poms-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-21 22:46:30","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":407801,"slug":"une-efficacite-elevee-precoce-cle-de-lamelioration-du-pronostic","post_title":"Une efficacit\u00e9 \u00e9lev\u00e9e pr\u00e9coce, cl\u00e9 de l'am\u00e9lioration du pronostic","href":"https:\/\/medizinonline.com\/fr\/une-efficacite-elevee-precoce-cle-de-lamelioration-du-pronostic\/"},"it_IT":{"locale":"it_IT","id":407798,"slug":"lalta-efficacia-precoce-come-chiave-per-migliorare-la-prognosi","post_title":"L'alta efficacia precoce come chiave per migliorare la prognosi","href":"https:\/\/medizinonline.com\/it\/lalta-efficacia-precoce-come-chiave-per-migliorare-la-prognosi\/"},"pt_PT":{"locale":"pt_PT","id":407810,"slug":"a-alta-eficacia-precoce-como-chave-para-melhorar-o-prognostico","post_title":"A alta efic\u00e1cia precoce como chave para melhorar o progn\u00f3stico","href":"https:\/\/medizinonline.com\/pt-pt\/a-alta-eficacia-precoce-como-chave-para-melhorar-o-prognostico\/"},"es_ES":{"locale":"es_ES","id":407807,"slug":"alta-eficacia-precoz-como-clave-para-mejorar-el-pronostico","post_title":"Alta eficacia precoz como clave para mejorar el pron\u00f3stico","href":"https:\/\/medizinonline.com\/es\/alta-eficacia-precoz-como-clave-para-mejorar-el-pronostico\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=407747"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407747\/revisions"}],"predecessor-version":[{"id":407753,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407747\/revisions\/407753"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/407751"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=407747"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=407747"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=407747"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=407747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}