{"id":407775,"date":"2025-10-26T00:16:05","date_gmt":"2025-10-25T22:16:05","guid":{"rendered":"https:\/\/medizinonline.com\/ageing-cellular-senescence-and-parkinsons-disease\/"},"modified":"2025-10-26T00:16:11","modified_gmt":"2025-10-25T22:16:11","slug":"ageing-cellular-senescence-and-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/ageing-cellular-senescence-and-parkinsons-disease\/","title":{"rendered":"Ageing, cellular senescence and Parkinson&#8217;s disease"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Parkinson&#8217;s is one of the most common neurodegenerative diseases and continues to pose major challenges for neurology. It has long been clear that age is the decisive risk factor &#8211; but the mechanisms of how biological ageing and neuronal degeneration interact have so far been incompletely understood. In recent years, a cellular process has increasingly become the focus of research: senescence. It describes a state of irreversible cell cycle arrest, accompanied by profound metabolic changes and a pro-inflammatory secretion profile.   <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fageing-cellular-senescence-and-parkinsons-disease%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Parkinson&#8217;s is one of the most common neurodegenerative diseases and continues to pose major challenges for neurology. It has long been clear that age is the decisive risk factor &#8211;&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fageing-cellular-senescence-and-parkinsons-disease%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":407781,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"New perspectives for clinics and research  ","footnotes":""},"category":[11508,11347,11363,11548],"tags":[11747,72202],"powerkit_post_featured":[],"class_list":["post-407775","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-geriatrics","category-neurology","category-rx-en","tag-parkinsons","tag-senescence","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-17 02:10:49","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":407767,"slug":"vieillissement-senescence-cellulaire-et-maladie-de-parkinson","post_title":"Vieillissement, s\u00e9nescence cellulaire et maladie de Parkinson","href":"https:\/\/medizinonline.com\/fr\/vieillissement-senescence-cellulaire-et-maladie-de-parkinson\/"},"it_IT":{"locale":"it_IT","id":407759,"slug":"invecchiamento-senescenza-cellulare-e-malattia-di-parkinson","post_title":"Invecchiamento, senescenza cellulare e malattia di Parkinson","href":"https:\/\/medizinonline.com\/it\/invecchiamento-senescenza-cellulare-e-malattia-di-parkinson\/"},"pt_PT":{"locale":"pt_PT","id":407752,"slug":"envelhecimento-senescencia-celular-e-doenca-de-parkinson","post_title":"Envelhecimento, senesc\u00eancia celular e doen\u00e7a de Parkinson","href":"https:\/\/medizinonline.com\/pt-pt\/envelhecimento-senescencia-celular-e-doenca-de-parkinson\/"},"es_ES":{"locale":"es_ES","id":407804,"slug":"envejecimiento-senescencia-celular-y-enfermedad-de-parkinson","post_title":"Envejecimiento, senescencia celular y enfermedad de Parkinson","href":"https:\/\/medizinonline.com\/es\/envejecimiento-senescencia-celular-y-enfermedad-de-parkinson\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407775","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=407775"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407775\/revisions"}],"predecessor-version":[{"id":407782,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/407775\/revisions\/407782"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/407781"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=407775"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=407775"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=407775"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=407775"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}