{"id":408386,"date":"2025-09-26T13:30:00","date_gmt":"2025-09-26T11:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=408386"},"modified":"2025-09-11T10:23:59","modified_gmt":"2025-09-11T08:23:59","slug":"advances-in-breast-cancer-therapy-in-the-age-of-molecular-diagnostics","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/advances-in-breast-cancer-therapy-in-the-age-of-molecular-diagnostics\/","title":{"rendered":"Advances in breast cancer therapy in the age of molecular diagnostics"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized therapy concepts are increasingly determining treatment today. Multigenomic signatures, next-generation sequencing and liquid biopsy have redefined risk stratification. At the same time, targeted drugs have been developed that intervene precisely in oncogenic signaling pathways. In addition, antibody-drug conjugates and immune checkpoint inhibitors are expanding the therapeutic spectrum.    <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fadvances-in-breast-cancer-therapy-in-the-age-of-molecular-diagnostics%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fadvances-in-breast-cancer-therapy-in-the-age-of-molecular-diagnostics%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":408388,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"From genome profiles to targeted therapies  ","footnotes":""},"category":[11548,11508,11396,11400,11370,11460,11503],"tags":[27538,13554,13561,16452,85228],"powerkit_post_featured":[],"class_list":["post-408386","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-education","category-genetics","category-gynecology","category-oncology","category-prevention-and-health-care","category-studies","tag-brca-en","tag-breast-cancer-en","tag-breast-cancer-en-2","tag-her2-en","tag-liquid-biobsy-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-04 17:37:55","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":408380,"slug":"progres-dans-le-traitement-du-cancer-du-sein-a-lere-du-diagnostic-moleculaire","post_title":"Progr\u00e8s dans le traitement du cancer du sein \u00e0 l'\u00e8re du diagnostic mol\u00e9culaire","href":"https:\/\/medizinonline.com\/fr\/progres-dans-le-traitement-du-cancer-du-sein-a-lere-du-diagnostic-moleculaire\/"},"it_IT":{"locale":"it_IT","id":408407,"slug":"i-progressi-nella-terapia-del-tumore-al-seno-nellera-della-diagnostica-molecolare","post_title":"I progressi nella terapia del tumore al seno nell'era della diagnostica molecolare","href":"https:\/\/medizinonline.com\/it\/i-progressi-nella-terapia-del-tumore-al-seno-nellera-della-diagnostica-molecolare\/"},"pt_PT":{"locale":"pt_PT","id":408374,"slug":"avancos-na-terapia-do-cancro-da-mama-na-era-do-diagnostico-molecular","post_title":"Avan\u00e7os na terapia do cancro da mama na era do diagn\u00f3stico molecular","href":"https:\/\/medizinonline.com\/pt-pt\/avancos-na-terapia-do-cancro-da-mama-na-era-do-diagnostico-molecular\/"},"es_ES":{"locale":"es_ES","id":408421,"slug":"avances-en-la-terapia-del-cancer-de-mama-en-la-era-del-diagnostico-molecular","post_title":"Avances en la terapia del c\u00e1ncer de mama en la era del diagn\u00f3stico molecular","href":"https:\/\/medizinonline.com\/es\/avances-en-la-terapia-del-cancer-de-mama-en-la-era-del-diagnostico-molecular\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=408386"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408386\/revisions"}],"predecessor-version":[{"id":408390,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408386\/revisions\/408390"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/408388"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=408386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=408386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=408386"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=408386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}