{"id":408645,"date":"2025-11-02T00:30:00","date_gmt":"2025-11-01T23:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=408645"},"modified":"2025-10-23T09:20:32","modified_gmt":"2025-10-23T07:20:32","slug":"improvement-in-either-weight-or-hba1c-but-never-both","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/improvement-in-either-weight-or-hba1c-but-never-both\/","title":{"rendered":"Improvement in either weight or HbA1c &#8211; but never both"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Numerous studies show that glucagon-like peptide-1 receptor agonists (GLP1-RA) can significantly reduce the risk of diabetes-related complications and also reduce mortality. Despite their proven efficacy in trial designs, patient response to GLP1-RA therapy in the real world remains highly variable, particularly in terms of glycemic control and weight loss. The reasons for these variations and their relationship to specific patient characteristics are still unclear in clinical practice.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fimprovement-in-either-weight-or-hba1c-but-never-both%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Numerous studies show that glucagon-like peptide-1 receptor agonists (GLP1-RA) can significantly reduce the risk of diabetes-related complications and also reduce mortality. Despite their proven efficacy in trial designs, patient response&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fimprovement-in-either-weight-or-hba1c-but-never-both%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":408647,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"GLP1-RA therapy  ","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11548,11508,11384,11442,11503],"tags":[74206,85278,15896,74238,80048,12042,52156],"powerkit_post_featured":[],"class_list":["post-408645","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-education","category-endocrinology-and-diabetology","category-pharmacology-and-toxicology","category-studies","tag-glp1-ra-en","tag-glucagon-like-peptide-1-receptor-agonists-en","tag-glycemic-control","tag-hba1c-value","tag-t2d-en","tag-type-2-diabetes","tag-weight-loss-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-09-06 11:15:51","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":408639,"slug":"amelioration-soit-du-poids-soit-de-lhba1c-mais-jamais-des-deux","post_title":"Am\u00e9lioration soit du poids, soit de l'HbA1c - mais jamais des deux","href":"https:\/\/medizinonline.com\/fr\/amelioration-soit-du-poids-soit-de-lhba1c-mais-jamais-des-deux\/"},"it_IT":{"locale":"it_IT","id":408634,"slug":"miglioramento-del-peso-o-dellhba1c-ma-mai-di-entrambi","post_title":"Miglioramento del peso o dell'HbA1c, ma mai di entrambi.","href":"https:\/\/medizinonline.com\/it\/miglioramento-del-peso-o-dellhba1c-ma-mai-di-entrambi\/"},"pt_PT":{"locale":"pt_PT","id":408628,"slug":"melhoria-do-peso-ou-da-hba1c-mas-nunca-de-ambos","post_title":"Melhoria do peso ou da HbA1c - mas nunca de ambos","href":"https:\/\/medizinonline.com\/pt-pt\/melhoria-do-peso-ou-da-hba1c-mas-nunca-de-ambos\/"},"es_ES":{"locale":"es_ES","id":408621,"slug":"mejora-del-peso-o-de-la-hba1c-pero-nunca-de-ambos","post_title":"Mejora del peso o de la HbA1c - pero nunca de ambos","href":"https:\/\/medizinonline.com\/es\/mejora-del-peso-o-de-la-hba1c-pero-nunca-de-ambos\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=408645"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408645\/revisions"}],"predecessor-version":[{"id":408649,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/408645\/revisions\/408649"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/408647"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=408645"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=408645"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=408645"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=408645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}