{"id":410910,"date":"2025-12-04T00:30:00","date_gmt":"2025-12-03T23:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=410910"},"modified":"2025-12-03T17:30:06","modified_gmt":"2025-12-03T16:30:06","slug":"brain-atrophy-correlates-with-disability-progression-in-ms","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/brain-atrophy-correlates-with-disability-progression-in-ms\/","title":{"rendered":"Brain atrophy correlates with disability progression in MS"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Brain atrophy in MS patients, particularly in the thalamus, correlates strongly with long-term physical disability and cognitive deficits. A long-term analysis of the phase 3 studies RADIANCE\/SUNBEAM and the open-label extension DAYBREAK now examines the efficacy of ozanimod over seven years. The results confirm sustained protection against volume loss and highlight the predictive role of brain volume biomarkers.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fbrain-atrophy-correlates-with-disability-progression-in-ms%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Brain atrophy in MS patients, particularly in the thalamus, correlates strongly with long-term physical disability and cognitive deficits. A long-term analysis of the phase 3 studies RADIANCE\/SUNBEAM and the open-label&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fbrain-atrophy-correlates-with-disability-progression-in-ms%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":410911,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Brain atrophy and MS","footnotes":""},"category":[11548,11508,11363,11503],"tags":[55705,12354,35781],"powerkit_post_featured":[],"class_list":["post-410910","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-education","category-neurology","category-studies","tag-brain-atrophy","tag-multiple-sclerosis","tag-ozanimod-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-25 17:19:29","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":410858,"slug":"latrophie-cerebrale-est-correlee-a-la-progression-de-linvalidite-dans-la-sep","post_title":"L'atrophie c\u00e9r\u00e9brale est corr\u00e9l\u00e9e \u00e0 la progression de l'invalidit\u00e9 dans la SEP","href":"https:\/\/medizinonline.com\/fr\/latrophie-cerebrale-est-correlee-a-la-progression-de-linvalidite-dans-la-sep\/"},"it_IT":{"locale":"it_IT","id":410866,"slug":"latrofia-cerebrale-si-correla-con-la-progressione-della-disabilita-nella-sm","post_title":"L'atrofia cerebrale si correla con la progressione della disabilit\u00e0 nella SM","href":"https:\/\/medizinonline.com\/it\/latrofia-cerebrale-si-correla-con-la-progressione-della-disabilita-nella-sm\/"},"pt_PT":{"locale":"pt_PT","id":410855,"slug":"a-atrofia-cerebral-esta-correlacionada-com-a-progressao-da-incapacidade-na-em","post_title":"A atrofia cerebral est\u00e1 correlacionada com a progress\u00e3o da incapacidade na EM","href":"https:\/\/medizinonline.com\/pt-pt\/a-atrofia-cerebral-esta-correlacionada-com-a-progressao-da-incapacidade-na-em\/"},"es_ES":{"locale":"es_ES","id":410854,"slug":"la-atrofia-cerebral-se-correlaciona-con-la-progresion-de-la-discapacidad-en-la-em","post_title":"La atrofia cerebral se correlaciona con la progresi\u00f3n de la discapacidad en la EM","href":"https:\/\/medizinonline.com\/es\/la-atrofia-cerebral-se-correlaciona-con-la-progresion-de-la-discapacidad-en-la-em\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/410910","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=410910"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/410910\/revisions"}],"predecessor-version":[{"id":410912,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/410910\/revisions\/410912"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/410911"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=410910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=410910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=410910"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=410910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}