{"id":411347,"date":"2025-11-07T13:30:00","date_gmt":"2025-11-07T12:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/advantages-of-early-biologic-therapy-and-oral-peptide-as-a-beacon-of-hope\/"},"modified":"2025-11-07T14:35:29","modified_gmt":"2025-11-07T13:35:29","slug":"advantages-of-early-biologic-therapy-and-oral-peptide-as-a-beacon-of-hope","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/advantages-of-early-biologic-therapy-and-oral-peptide-as-a-beacon-of-hope\/","title":{"rendered":"Advantages of early biologic therapy and oral peptide as a beacon of hope"},"content":{"rendered":"\n<p><strong>The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding effects of guselkumab therapy and came up with some interesting findings. Memory T cells appear to play a key role in the long-term modification of the course of the disease. In addition to subcutaneously applied biologics, which are currently considered the gold standard of systemic treatment for psoriasis, promising data is now also available on the orally applied peptide Icotrokinra.     <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fadvantages-of-early-biologic-therapy-and-oral-peptide-as-a-beacon-of-hope%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fadvantages-of-early-biologic-therapy-and-oral-peptide-as-a-beacon-of-hope%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":411350,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Psoriasis: intervening in the inflammatory cascade  ","footnotes":""},"category":[11513,11340,11442,11480,11548,11503],"tags":[65706,85919,17853,82357,18157,84534,65720,84532,14032,12536,36635,23439],"powerkit_post_featured":[],"class_list":["post-411347","post","type-post","status-publish","format-standard","has-post-thumbnail","category-congress-reports","category-dermatology-and-venereology","category-pharmacology-and-toxicology","category-rheumatology","category-rx-en","category-studies","tag-annual-congress","tag-biologic-therapy","tag-cosentyx-en","tag-guide-en","tag-guselkumab-en","tag-icotrokinra-en","tag-inflammatory-cascade","tag-oral-peptide","tag-psoriasis-en-2","tag-secukinumab-en","tag-sgdv-en","tag-tremfya-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-01 06:31:58","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":411343,"slug":"avantages-dun-traitement-biologique-precoce-et-peptide-oral-porteur-despoir","post_title":"Avantages d'un traitement biologique pr\u00e9coce et peptide oral porteur d'espoir","href":"https:\/\/medizinonline.com\/fr\/avantages-dun-traitement-biologique-precoce-et-peptide-oral-porteur-despoir\/"},"it_IT":{"locale":"it_IT","id":411337,"slug":"vantaggi-della-terapia-biologica-precoce-e-peptide-orale-come-faro-di-speranza","post_title":"Vantaggi della terapia biologica precoce e peptide orale come faro di speranza","href":"https:\/\/medizinonline.com\/it\/vantaggi-della-terapia-biologica-precoce-e-peptide-orale-come-faro-di-speranza\/"},"pt_PT":{"locale":"pt_PT","id":411334,"slug":"vantagens-da-terapeutica-biologica-precoce-e-do-peptido-oral-como-um-sinal-de-esperanca","post_title":"Vantagens da terap\u00eautica biol\u00f3gica precoce e do p\u00e9ptido oral como um sinal de esperan\u00e7a","href":"https:\/\/medizinonline.com\/pt-pt\/vantagens-da-terapeutica-biologica-precoce-e-do-peptido-oral-como-um-sinal-de-esperanca\/"},"es_ES":{"locale":"es_ES","id":411360,"slug":"ventajas-de-la-terapia-biologica-precoz-y-el-peptido-oral-como-faro-de-esperanza","post_title":"Ventajas de la terapia biol\u00f3gica precoz y el p\u00e9ptido oral como faro de esperanza","href":"https:\/\/medizinonline.com\/es\/ventajas-de-la-terapia-biologica-precoz-y-el-peptido-oral-como-faro-de-esperanza\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=411347"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411347\/revisions"}],"predecessor-version":[{"id":411351,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411347\/revisions\/411351"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/411350"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=411347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=411347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=411347"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=411347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}