{"id":411756,"date":"2025-11-30T13:30:00","date_gmt":"2025-11-30T12:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=411756"},"modified":"2025-11-29T08:40:03","modified_gmt":"2025-11-29T07:40:03","slug":"molecular-diversity-of-the-pdac","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/molecular-diversity-of-the-pdac\/","title":{"rendered":"Molecular diversity of the PDAC"},"content":{"rendered":"\n<p><strong>Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors of all. The five-year survival rate is still in the single digits. In recent years, however, there has been a paradigm shift: PDAC is no longer seen as a uniform disease, but as an ensemble of different molecular subtypes with clearly distinguishable biology. New genome, transcriptome, proteome, metabolome and immunome analyses are fundamentally changing our understanding of these tumors &#8211; and opening up prospects for more precise, individually targeted therapy.   <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmolecular-diversity-of-the-pdac%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors of all. The five-year survival rate is still in the single digits. In recent years, however, there has been&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmolecular-diversity-of-the-pdac%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":411761,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Subtyping as the key to precision medicine  ","footnotes":""},"category":[11508,11391,11396,11370,11548,11503],"tags":[49454,22957,21064,86067,86066],"powerkit_post_featured":[],"class_list":["post-411756","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-gastroenterology-and-hepatology","category-genetics","category-oncology","category-rx-en","category-studies","tag-cdkn2a-en","tag-kras-en","tag-pancreatic-cancer","tag-pdac","tag-smad4","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-03 01:00:30","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":411760,"slug":"diversite-moleculaire-du-pdac","post_title":"Diversit\u00e9 mol\u00e9culaire du PDAC","href":"https:\/\/medizinonline.com\/fr\/diversite-moleculaire-du-pdac\/"},"it_IT":{"locale":"it_IT","id":411757,"slug":"diversita-molecolare-del-pdac","post_title":"Diversit\u00e0 molecolare del PDAC","href":"https:\/\/medizinonline.com\/it\/diversita-molecolare-del-pdac\/"},"pt_PT":{"locale":"pt_PT","id":411758,"slug":"diversidade-molecular-do-pdac","post_title":"Diversidade molecular do PDAC","href":"https:\/\/medizinonline.com\/pt-pt\/diversidade-molecular-do-pdac\/"},"es_ES":{"locale":"es_ES","id":411759,"slug":"diversidad-molecular-del-pdac","post_title":"Diversidad molecular del PDAC","href":"https:\/\/medizinonline.com\/es\/diversidad-molecular-del-pdac\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411756","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=411756"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411756\/revisions"}],"predecessor-version":[{"id":411762,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/411756\/revisions\/411762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/411761"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=411756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=411756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=411756"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=411756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}