{"id":411896,"date":"2025-12-11T00:30:00","date_gmt":"2025-12-10T23:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/new-perspectives-in-first-line-therapy\/"},"modified":"2025-12-10T21:16:04","modified_gmt":"2025-12-10T20:16:04","slug":"new-perspectives-in-first-line-therapy","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/new-perspectives-in-first-line-therapy\/","title":{"rendered":"New perspectives in first-line therapy"},"content":{"rendered":"\n<p><strong>At this year&#8217;s IASLC <em>World Conference on Lung Cancer<\/em> (WCLC 2025) in Barcelona, a poster on the FLAURA2 study was presented, which presented new data on combination therapy with osimertinib in first-line EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC).<em> <\/em>The study showed that<em> <\/em>osimertinib in combination with chemotherapy consisting of pemetrexed with cisplatin or carboplatin reduced the risk of death by 23% compared to monotherapy with generally manageable side effects.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fnew-perspectives-in-first-line-therapy%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>At this year&#8217;s IASLC World Conference on Lung Cancer (WCLC 2025) in Barcelona, a poster on the FLAURA2 study was presented, which presented new data on combination therapy with osimertinib&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fnew-perspectives-in-first-line-therapy%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":411901,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Lung cancer with EGFR mutation","footnotes":"[{\"id\":\"e88b0f85-a52c-4cc0-be2c-2e37b16bcaa3\",\"content\":\"<a href=\\\"http:\\\/\\\/www.swissmedic.ch\\\/swissmedic\\\/de\\\/home\\\/humanarzneimittel\\\/authorisations\\\/new-medicines.html\\\" target=\\\"_blank\\\" rel=\\\"noreferrer noopener\\\">www.swissmedic.ch\\\/swissmedic\\\/de\\\/home\\\/humanarzneimittel\\\/authorisations\\\/new-medicines.html<\\\/a><br><a href=\\\"http:\\\/\\\/www.ema.europa.eu\\\/en\\\/documents\\\/overview\\\/tagrisso-epar-medicine-overview_en.pdf\\\" target=\\\"_blank\\\" rel=\\\"noreferrer noopener\\\">www.ema.europa.eu\\\/en\\\/documents\\\/overview\\\/tagrisso-epar-medicine-overview_en.pdf<\\\/a>\"}]"},"category":[11513,11370,11455,11548,11503],"tags":[57799,83869,86217,86220,86223,86219,86222],"powerkit_post_featured":[],"class_list":["post-411896","post","type-post","status-publish","format-standard","has-post-thumbnail","category-congress-reports","category-oncology","category-pneumology","category-rx-en","category-studies","tag-carboplatin-en","tag-cisplatin-en","tag-egfrm-nsclc","tag-flaura-2","tag-flaura2","tag-osimertinib-combination-therapy","tag-pemetrexed","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-15 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