{"id":412631,"date":"2025-12-04T13:30:00","date_gmt":"2025-12-04T12:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=412631"},"modified":"2026-01-20T11:08:24","modified_gmt":"2026-01-20T10:08:24","slug":"when-the-biologic-has-a-counterproductive-effect","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/when-the-biologic-has-a-counterproductive-effect\/","title":{"rendered":"When the biologic has a counterproductive effect"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Eosinophilic vasculitis with polyangiitis (EGPA) is a rare inflammation of small blood vessels that is usually associated with asthma. Eye involvement occurs sporadically and central retinal artery occlusion (CRAO) is an extremely rare but serious complication. During treatment with benralizumab, an EGPA with bilateral CRAO occurred.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhen-the-biologic-has-a-counterproductive-effect%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Eosinophilic vasculitis with polyangiitis (EGPA) is a rare inflammation of small blood vessels that is usually associated with asthma. Eye involvement occurs sporadically and central retinal artery occlusion (CRAO) is&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhen-the-biologic-has-a-counterproductive-effect%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":412634,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Benralizumab in a patient with asthma and EGPA  ","footnotes":""},"category":[11520,11508,11297,11423,11455,11480,11548],"tags":[12318,74929,80506,35653,86430,69753,86431],"powerkit_post_featured":[],"class_list":["post-412631","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cases-en","category-education","category-general-internal-medicine","category-ophthalmology","category-pneumology","category-rheumatology","category-rx-en","tag-asthma-en","tag-benralizumab-en","tag-biologics-therapy","tag-complications","tag-crao","tag-egpa-en","tag-eosinophilic-vasculitis-with-polyangiitis","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-11 09:43:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":412636,"slug":"si-le-medicament-biologique-a-un-effet-contre-productif","post_title":"Si le m\u00e9dicament biologique a un effet contre-productif","href":"https:\/\/medizinonline.com\/fr\/si-le-medicament-biologique-a-un-effet-contre-productif\/"},"it_IT":{"locale":"it_IT","id":412639,"slug":"quando-il-biologico-ha-un-effetto-controproducente","post_title":"Quando il biologico ha un effetto controproducente","href":"https:\/\/medizinonline.com\/it\/quando-il-biologico-ha-un-effetto-controproducente\/"},"pt_PT":{"locale":"pt_PT","id":412638,"slug":"quando-o-medicamento-biologico-tem-um-efeito-contraproducente","post_title":"Quando o medicamento biol\u00f3gico tem um efeito contraproducente","href":"https:\/\/medizinonline.com\/pt-pt\/quando-o-medicamento-biologico-tem-um-efeito-contraproducente\/"},"es_ES":{"locale":"es_ES","id":412713,"slug":"cuando-el-biologico-tiene-un-efecto-contraproducente","post_title":"Cuando el biol\u00f3gico tiene un efecto contraproducente","href":"https:\/\/medizinonline.com\/es\/cuando-el-biologico-tiene-un-efecto-contraproducente\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/412631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=412631"}],"version-history":[{"count":2,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/412631\/revisions"}],"predecessor-version":[{"id":460909,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/412631\/revisions\/460909"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/412634"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=412631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=412631"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=412631"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=412631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}