{"id":449817,"date":"2025-12-09T13:15:00","date_gmt":"2025-12-09T12:15:00","guid":{"rendered":"https:\/\/medizinonline.com\/effects-on-disease-associated-microglia-subpopulations\/"},"modified":"2025-12-09T17:03:19","modified_gmt":"2025-12-09T16:03:19","slug":"effects-on-disease-associated-microglia-subpopulations","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/effects-on-disease-associated-microglia-subpopulations\/","title":{"rendered":"Effects on disease-associated microglia subpopulations"},"content":{"rendered":"\n<p><strong>During the progression of Alzheimer&#8217;s disease, microglial cells located in the vicinity of plaques become overactivated and release cytotoxic mediators such as TNF\u03b1. In an animal study published in 2025, Nguyen et al. were able to show, among other things, that increased TNF\u03b1 levels in 5xFAD mice could be normalized by a five-week administration of EGb-761\u00ae-containing feed and that an influence on microglia subpopulations contributed to this effect.    <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Feffects-on-disease-associated-microglia-subpopulations%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>During the progression of Alzheimer&#8217;s disease, microglial cells located in the vicinity of plaques become overactivated and release cytotoxic mediators such as TNF\u03b1. In an animal study published in 2025,&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Feffects-on-disease-associated-microglia-subpopulations%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":458499,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Ginkgo biloba extract in the Alzheimer's mouse model  ","footnotes":""},"category":[11508,11297,11347,11363,11447,74319,11548,11503],"tags":[706,86964,3157,4159,79008,86966],"powerkit_post_featured":[],"class_list":["post-449817","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-general-internal-medicine","category-geriatrics","category-neurology","category-pharmaceutical-medicine","category-phytotherapy","category-rx-en","category-studies","tag-alzheimer","tag-alzheimers-mouse-model","tag-egb-761","tag-ginkgo","tag-ginkgo-biloba-extract","tag-microglia-subpopulations","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-02 13:33:15","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":449729,"slug":"effets-sur-les-sous-populations-microgliales-associees-a-la-maladie","post_title":"Effets sur les sous-populations microgliales associ\u00e9es \u00e0 la maladie","href":"https:\/\/medizinonline.com\/fr\/effets-sur-les-sous-populations-microgliales-associees-a-la-maladie\/"},"it_IT":{"locale":"it_IT","id":449809,"slug":"effetti-sulle-sottopopolazioni-di-microglia-associate-alla-malattia","post_title":"Effetti sulle sottopopolazioni di microglia associate alla malattia","href":"https:\/\/medizinonline.com\/it\/effetti-sulle-sottopopolazioni-di-microglia-associate-alla-malattia\/"},"pt_PT":{"locale":"pt_PT","id":449804,"slug":"efeitos-nas-subpopulacoes-de-microglia-associadas-a-doencas","post_title":"Efeitos nas subpopula\u00e7\u00f5es de microglia associadas a doen\u00e7as","href":"https:\/\/medizinonline.com\/pt-pt\/efeitos-nas-subpopulacoes-de-microglia-associadas-a-doencas\/"},"es_ES":{"locale":"es_ES","id":449798,"slug":"efectos-sobre-las-subpoblaciones-de-microglia-asociadas-a-la-enfermedad","post_title":"Efectos sobre las subpoblaciones de microgl\u00eda asociadas a la enfermedad","href":"https:\/\/medizinonline.com\/es\/efectos-sobre-las-subpoblaciones-de-microglia-asociadas-a-la-enfermedad\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/449817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=449817"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/449817\/revisions"}],"predecessor-version":[{"id":449820,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/449817\/revisions\/449820"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/458499"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=449817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=449817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=449817"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=449817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}