{"id":459730,"date":"2026-01-23T13:35:00","date_gmt":"2026-01-23T12:35:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=459730"},"modified":"2026-01-23T12:32:37","modified_gmt":"2026-01-23T11:32:37","slug":"innovative-method-for-predicting-therapy-response","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/innovative-method-for-predicting-therapy-response\/","title":{"rendered":"Innovative method for predicting therapy response"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Until now, it was assumed that TVEC works by activating T cells. However, in a study by British and US scientists published in <em>JCO Oncology Advances<\/em>, the T cell populations showed no correlation with the success of the therapy. Instead, they found that changes in macrophages correlated with treatment response. Their pilot study used a FRET assay (iFRET), a novel tool for identifying biomarkers.     <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Finnovative-method-for-predicting-therapy-response%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Until now, it was assumed that TVEC works by activating T cells. However, in a study by British and US scientists published in JCO Oncology Advances, the T cell populations&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Finnovative-method-for-predicting-therapy-response%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":459732,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Oncolytic virus in stage II melanoma","footnotes":""},"category":[11340,11508,11370,11548,11503],"tags":[13687,87575,87574,87579,16535,12348,87577,71564,87576,87573,87578],"powerkit_post_featured":[],"class_list":["post-459730","post","type-post","status-publish","format-standard","has-post-thumbnail","category-dermatology-and-venereology","category-education","category-oncology","category-rx-en","category-studies","tag-biomarker-en","tag-fret-assay","tag-ifret","tag-jco-oncology-advances","tag-macrophages","tag-melanoma-en","tag-oncolytic-virus","tag-pilot-study","tag-stage-ii","tag-t-cell-populations","tag-vec","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-11 21:11:42","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":459748,"slug":"une-methode-innovante-pour-predire-la-reponse-au-traitement","post_title":"Une m\u00e9thode innovante pour pr\u00e9dire la r\u00e9ponse au traitement","href":"https:\/\/medizinonline.com\/fr\/une-methode-innovante-pour-predire-la-reponse-au-traitement\/"},"it_IT":{"locale":"it_IT","id":459739,"slug":"metodo-innovativo-per-prevedere-la-risposta-alla-terapia","post_title":"Metodo innovativo per prevedere la risposta alla terapia","href":"https:\/\/medizinonline.com\/it\/metodo-innovativo-per-prevedere-la-risposta-alla-terapia\/"},"pt_PT":{"locale":"pt_PT","id":459731,"slug":"metodo-inovador-para-prever-a-resposta-a-terapia","post_title":"M\u00e9todo inovador para prever a resposta \u00e0 terapia","href":"https:\/\/medizinonline.com\/pt-pt\/metodo-inovador-para-prever-a-resposta-a-terapia\/"},"es_ES":{"locale":"es_ES","id":459740,"slug":"metodo-innovador-para-predecir-la-respuesta-terapeutica","post_title":"M\u00e9todo innovador para predecir la respuesta terap\u00e9utica","href":"https:\/\/medizinonline.com\/es\/metodo-innovador-para-predecir-la-respuesta-terapeutica\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/459730","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=459730"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/459730\/revisions"}],"predecessor-version":[{"id":459733,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/459730\/revisions\/459733"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/459732"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=459730"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=459730"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=459730"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=459730"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}