{"id":460494,"date":"2026-02-13T21:39:23","date_gmt":"2026-02-13T20:39:23","guid":{"rendered":"https:\/\/medizinonline.com\/immunosenescence-and-inflammaging\/"},"modified":"2026-02-13T21:39:30","modified_gmt":"2026-02-13T20:39:30","slug":"immunosenescence-and-inflammaging","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/immunosenescence-and-inflammaging\/","title":{"rendered":"Immunosenescence and inflammaging"},"content":{"rendered":"\n<p><strong>Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated &#8211; with consequences for susceptibility to infection, tumor development and the large group of inflammation-driven cardiometabolic diseases. In the following, central molecular mechanisms, clinical manifestations and potential intervention approaches are summarized based on current reviews and primary studies on immunosenescence, chronic inflammation and age-associated diseases.    <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fimmunosenescence-and-inflammaging%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated &#8211; with consequences for susceptibility to infection,&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fimmunosenescence-and-inflammaging%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":460495,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Chronic inflammation as a driver of ageing","footnotes":""},"category":[11508,11297,11396,11347,11370,11460,11548,11503],"tags":[],"powerkit_post_featured":[],"class_list":["post-460494","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-general-internal-medicine","category-genetics","category-geriatrics","category-oncology","category-prevention-and-health-care","category-rx-en","category-studies","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-19 17:14:57","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":460497,"slug":"immunosenescence-et-inflammation","post_title":"Immunos\u00e9nescence et inflammation","href":"https:\/\/medizinonline.com\/fr\/immunosenescence-et-inflammation\/"},"it_IT":{"locale":"it_IT","id":460563,"slug":"immunosenescenza-e-infiammazione","post_title":"Immunosenescenza e infiammazione","href":"https:\/\/medizinonline.com\/it\/immunosenescenza-e-infiammazione\/"},"pt_PT":{"locale":"pt_PT","id":460560,"slug":"imunossenescencia-e-inflamacao","post_title":"Imunossenesc\u00eancia e inflama\u00e7\u00e3o","href":"https:\/\/medizinonline.com\/pt-pt\/imunossenescencia-e-inflamacao\/"},"es_ES":{"locale":"es_ES","id":460581,"slug":"inmunosenescencia-e-inflamacion","post_title":"Inmunosenescencia e inflamaci\u00f3n","href":"https:\/\/medizinonline.com\/es\/inmunosenescencia-e-inflamacion\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=460494"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460494\/revisions"}],"predecessor-version":[{"id":460496,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460494\/revisions\/460496"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/460495"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=460494"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=460494"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=460494"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=460494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}