{"id":460551,"date":"2026-02-21T22:43:25","date_gmt":"2026-02-21T21:43:25","guid":{"rendered":"https:\/\/medizinonline.com\/epigenetic-ageing\/"},"modified":"2026-02-21T22:44:49","modified_gmt":"2026-02-21T21:44:49","slug":"epigenetic-ageing","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/epigenetic-ageing\/","title":{"rendered":"Epigenetic ageing"},"content":{"rendered":"\n<p><strong>In recent years, epigenetic clocks based on DNA methylation have evolved from research tools to widely used biomarkers of biological ageing. They correlate not only with chronological age, but also &#8211; depending on the &#8220;clock generation&#8221; &#8211; with morbidity, functional outcomes and mortality risks. At the same time, the step into clinical routine is challenging: measurement accuracy, comparability between tests, population generalizability and clinical decision limits have so far only been partially standardized.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fepigenetic-ageing%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>In recent years, epigenetic clocks based on DNA methylation have evolved from research tools to widely used biomarkers of biological ageing. They correlate not only with chronological age, but also&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fepigenetic-ageing%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":460552,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"What biomarkers reveal about \"biological youth\" - and what not (yet)","footnotes":""},"category":[11508,11396,11347,11460,11548,11503],"tags":[],"powerkit_post_featured":[],"class_list":["post-460551","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-genetics","category-geriatrics","category-prevention-and-health-care","category-rx-en","category-studies","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-06 00:48:38","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":460527,"slug":"vieillissement-epigenetique","post_title":"Vieillissement \u00e9pig\u00e9n\u00e9tique","href":"https:\/\/medizinonline.com\/fr\/vieillissement-epigenetique\/"},"it_IT":{"locale":"it_IT","id":460483,"slug":"invecchiamento-epigenetico","post_title":"Invecchiamento epigenetico","href":"https:\/\/medizinonline.com\/it\/invecchiamento-epigenetico\/"},"pt_PT":{"locale":"pt_PT","id":460524,"slug":"envelhecimento-epigenetico","post_title":"Envelhecimento epigen\u00e9tico","href":"https:\/\/medizinonline.com\/pt-pt\/envelhecimento-epigenetico\/"},"es_ES":{"locale":"es_ES","id":460521,"slug":"envejecimiento-epigenetico","post_title":"Envejecimiento epigen\u00e9tico","href":"https:\/\/medizinonline.com\/es\/envejecimiento-epigenetico\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=460551"}],"version-history":[{"count":2,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460551\/revisions"}],"predecessor-version":[{"id":550988,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/460551\/revisions\/550988"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/460552"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=460551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=460551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=460551"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=460551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}