{"id":461603,"date":"2026-02-14T12:30:00","date_gmt":"2026-02-14T11:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/standard-established-at-hfref-with-individual-nuances\/"},"modified":"2026-02-13T22:36:45","modified_gmt":"2026-02-13T21:36:45","slug":"standard-established-at-hfref-with-individual-nuances","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/standard-established-at-hfref-with-individual-nuances\/","title":{"rendered":"Standard established at HFrEF with individual nuances"},"content":{"rendered":"\n

The modern treatment of heart failure is characterized by early intervention, multidimensional care and extended therapy options. Around half of all heart failure patients have a reduced left ventricular ejection fraction. With regard to drug therapy, according to ESC guidelines, there are four standard recommended drug classes that should be used early in HFrEF, as they are particularly important for reducing morbidity and mortality. SGLT-2 inhibitors are now recommended for HFrEF, HFmrEF and HFpEF. <\/strong><\/p>\n\n

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The modern treatment of heart failure is characterized by early intervention, multidimensional care and extended therapy options. Around half of all heart failure patients have a reduced left ventricular ejection……... <\/p>\n

Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich
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Already a member? Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":461604,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Heart failure: combination of four as \"Guideline-Directed Medical Therapy\"","footnotes":""},"category":[11359,11513,11297,11413,11548,11503],"tags":[23436,88430,23494,29527,68418,88431,12130,64958,14577,14580,88432,68426,23627],"powerkit_post_featured":[],"class_list":["post-461603","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cardiology","category-congress-reports","category-general-internal-medicine","category-nephrology","category-rx-en","category-studies","tag-ace-inhibitors","tag-angiotensin-receptor-neprilysin-inhibitor","tag-arni-en","tag-beta-blocker-en","tag-combination-of-four","tag-guideline-directed-medical-therapy","tag-heart-failure-en","tag-heart-valve-disease","tag-hfmref-en","tag-hfref-en","tag-mineralocorticoid-receptor-antagonist-2","tag-mra-en","tag-sglt2-inhibitors","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-24 19:25:57","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":461600,"slug":"standard-etabli-au-hfref-avec-des-nuances-individuelles","post_title":"Standard \u00e9tabli au HFrEF avec des nuances individuelles","href":"https:\/\/medizinonline.com\/fr\/standard-etabli-au-hfref-avec-des-nuances-individuelles\/"},"it_IT":{"locale":"it_IT","id":461618,"slug":"uno-standard-consolidato-presso-hfref-con-sfumature-individuali","post_title":"Uno standard consolidato presso HFrEF con sfumature individuali.","href":"https:\/\/medizinonline.com\/it\/uno-standard-consolidato-presso-hfref-con-sfumature-individuali\/"},"pt_PT":{"locale":"pt_PT","id":461597,"slug":"padrao-estabelecido-no-hfref-com-nuances-individuais","post_title":"Padr\u00e3o estabelecido no HFrEF com nuances individuais","href":"https:\/\/medizinonline.com\/pt-pt\/padrao-estabelecido-no-hfref-com-nuances-individuais\/"},"es_ES":{"locale":"es_ES","id":461564,"slug":"norma-establecida-en-hfref-con-matices-individuales","post_title":"Norma establecida en HFrEF con matices individuales","href":"https:\/\/medizinonline.com\/es\/norma-establecida-en-hfref-con-matices-individuales\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/461603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=461603"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/461603\/revisions"}],"predecessor-version":[{"id":461605,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/461603\/revisions\/461605"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/461604"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=461603"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=461603"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=461603"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=461603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}