{"id":554010,"date":"2026-05-04T22:44:32","date_gmt":"2026-05-04T20:44:32","guid":{"rendered":"https:\/\/medizinonline.com\/?p=554010"},"modified":"2026-05-04T22:44:38","modified_gmt":"2026-05-04T20:44:38","slug":"new-pathophysiology-updated-diagnostics-and-the-age-of-incretin-mimetics","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/new-pathophysiology-updated-diagnostics-and-the-age-of-incretin-mimetics\/","title":{"rendered":"New pathophysiology, updated diagnostics and the age of incretin mimetics"},"content":{"rendered":"\n

With a prevalence of 8-13%, polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age – and yet up to 70% of those affected remain undiagnosed. In 2025 and 2026, new insights into the pathophysiology have fundamentally expanded the picture of PCOS: the gut-microbiome axis, the neuroendocrine gut-brain axis and chronic low-grade inflammation are playing an increasingly central role. At the same time, GLP-1 receptor agonists such as semaglutide and tirzepatide are experiencing a clinical breakthrough as an off-label option for PCOS with a metabolic phenotype. <\/strong><\/p>\n\n

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With a prevalence of 8-13%, polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age – and yet up to 70% of those affected remain……... <\/p>\n

Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich
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Already a member? Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":554011,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Polycystic ovary syndrome 2025\/2026","footnotes":""},"category":[11508,11391,11297,11400,11442,11548,11503],"tags":[91098,81064,91097,91099],"powerkit_post_featured":[],"class_list":["post-554010","post","type-post","status-publish","format-standard","has-post-thumbnail","category-education","category-gastroenterology-and-hepatology","category-general-internal-medicine","category-gynecology","category-pharmacology-and-toxicology","category-rx-en","category-studies","tag-amh","tag-pcos-en","tag-polycystic-ovary-syndrome","tag-rotterdam-criteria","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-12 02:58:25","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":553976,"slug":"nouvelle-physiopathologie-diagnostic-actualise-et-ere-des-incretino-mimetiques","post_title":"Nouvelle physiopathologie, diagnostic actualis\u00e9 et \u00e8re des incr\u00e9tino-mim\u00e9tiques","href":"https:\/\/medizinonline.com\/fr\/nouvelle-physiopathologie-diagnostic-actualise-et-ere-des-incretino-mimetiques\/"},"it_IT":{"locale":"it_IT","id":553973,"slug":"nuova-fisiopatologia-diagnostica-aggiornata-e-lera-dei-mimetici-dellincretina","post_title":"Nuova fisiopatologia, diagnostica aggiornata e l'era dei mimetici dell'incretina","href":"https:\/\/medizinonline.com\/it\/nuova-fisiopatologia-diagnostica-aggiornata-e-lera-dei-mimetici-dellincretina\/"},"pt_PT":{"locale":"pt_PT","id":553989,"slug":"nova-fisiopatologia-diagnosticos-actualizados-e-a-era-dos-mimeticos-da-incretina","post_title":"Nova fisiopatologia, diagn\u00f3sticos actualizados e a era dos mim\u00e9ticos da incretina","href":"https:\/\/medizinonline.com\/pt-pt\/nova-fisiopatologia-diagnosticos-actualizados-e-a-era-dos-mimeticos-da-incretina\/"},"es_ES":{"locale":"es_ES","id":553986,"slug":"nueva-fisiopatologia-diagnosticos-actualizados-y-la-era-de-los-mimeticos-de-la-incretina","post_title":"Nueva fisiopatolog\u00eda, diagn\u00f3sticos actualizados y la era de los mim\u00e9ticos de la incretina","href":"https:\/\/medizinonline.com\/es\/nueva-fisiopatologia-diagnosticos-actualizados-y-la-era-de-los-mimeticos-de-la-incretina\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=554010"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554010\/revisions"}],"predecessor-version":[{"id":554012,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554010\/revisions\/554012"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/554011"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=554010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=554010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=554010"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=554010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}