{"id":554587,"date":"2026-04-12T20:00:00","date_gmt":"2026-04-12T18:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/addressing-metabolic-drivers-and-counteracting-fibrosis\/"},"modified":"2026-04-17T17:46:04","modified_gmt":"2026-04-17T15:46:04","slug":"addressing-metabolic-drivers-and-counteracting-fibrosis","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/addressing-metabolic-drivers-and-counteracting-fibrosis\/","title":{"rendered":"Addressing metabolic drivers and counteracting fibrosis"},"content":{"rendered":"\n<p><strong>Steatotic liver diseases that are not associated with alcohol consumption are now referred to as metabolic steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). There is now no need for a liver biopsy to make a diagnosis, which is a great simplification in everyday practice. Treatment is still based on lifestyle modification, but with semaglutide and resmetirome there are two new promising pharmacotherapies, and gastric bypass and gastric sleeve surgery are also evidence-based interventions.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Faddressing-metabolic-drivers-and-counteracting-fibrosis%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Steatotic liver diseases that are not associated with alcohol consumption are now referred to as metabolic steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). There is now no need&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Faddressing-metabolic-drivers-and-counteracting-fibrosis%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":554588,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"MASLD\/MASH: lifestyle, pharmacotherapy, bariatric procedures","footnotes":""},"category":[11513,11391,11442,11548,11503,11380],"tags":[77356,83694,77506,11780,17444,82940,91393],"powerkit_post_featured":[],"class_list":["post-554587","post","type-post","status-publish","format-standard","has-post-thumbnail","category-congress-reports","category-gastroenterology-and-hepatology","category-pharmacology-and-toxicology","category-rx-en","category-studies","category-surgery","tag-lifestyle-modification-en","tag-mash-en-3","tag-masld-en","tag-pharmacotherapy","tag-semaglutide-en-2","tag-steatohepatitis-en","tag-steatotic-liver-diseases-2","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-25 06:29:34","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":554584,"slug":"sattaquer-aux-moteurs-metaboliques-et-contrer-la-fibrose","post_title":"S'attaquer aux moteurs m\u00e9taboliques et contrer la fibrose","href":"https:\/\/medizinonline.com\/fr\/sattaquer-aux-moteurs-metaboliques-et-contrer-la-fibrose\/"},"it_IT":{"locale":"it_IT","id":554581,"slug":"affrontare-i-driver-metabolici-e-contrastare-la-fibrosi","post_title":"Affrontare i driver metabolici e contrastare la fibrosi","href":"https:\/\/medizinonline.com\/it\/affrontare-i-driver-metabolici-e-contrastare-la-fibrosi\/"},"pt_PT":{"locale":"pt_PT","id":554578,"slug":"abordar-os-factores-metabolicos-e-combater-a-fibrose","post_title":"Abordar os factores metab\u00f3licos e combater a fibrose","href":"https:\/\/medizinonline.com\/pt-pt\/abordar-os-factores-metabolicos-e-combater-a-fibrose\/"},"es_ES":{"locale":"es_ES","id":554575,"slug":"abordar-los-impulsores-metabolicos-y-contrarrestar-la-fibrosis","post_title":"Abordar los impulsores metab\u00f3licos y contrarrestar la fibrosis","href":"https:\/\/medizinonline.com\/es\/abordar-los-impulsores-metabolicos-y-contrarrestar-la-fibrosis\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=554587"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554587\/revisions"}],"predecessor-version":[{"id":554589,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/554587\/revisions\/554589"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/554588"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=554587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=554587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=554587"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=554587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}