{"id":555259,"date":"2026-04-15T23:00:00","date_gmt":"2026-04-15T21:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/reaching-the-goal-with-innovative-therapy-strategies\/"},"modified":"2026-04-23T16:28:11","modified_gmt":"2026-04-23T14:28:11","slug":"reaching-the-goal-with-innovative-therapy-strategies","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/reaching-the-goal-with-innovative-therapy-strategies\/","title":{"rendered":"Reaching the goal with innovative therapy strategies"},"content":{"rendered":"\n<p><strong>The further development of patient-oriented, function-preserving treatment strategies is an important concern of skin cancer research. For patients with advanced cutaneous basal cell carcinoma (BCC), there is a need for alternative treatment options, as surgical excision alone may not be effective. Hedgehog inhibitors (HHI) are approved in certain cases of advanced BCC. Contrary to the guideline recommendation, this does not apply to the neoadjuvant setting, but case reports document the successful use of HHI in the neoadjuvant setting.   <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Freaching-the-goal-with-innovative-therapy-strategies%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The further development of patient-oriented, function-preserving treatment strategies is an important concern of skin cancer research. For patients with advanced cutaneous basal cell carcinoma (BCC), there is a need for&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Freaching-the-goal-with-innovative-therapy-strategies%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":555260,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"When basal cell carcinomas prove difficult to treat  ","footnotes":""},"category":[11520,11513,11340,11370,11548,11503,11380],"tags":[91648,91651,47335,91649,91650,91652,91653,24319],"powerkit_post_featured":[],"class_list":["post-555259","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cases-en","category-congress-reports","category-dermatology-and-venereology","category-oncology","category-rx-en","category-studies","category-surgery","tag-basal-cell-catinomas","tag-basaliomas","tag-bcc-en","tag-difficult-to-treat","tag-hedgehog-inhibitors","tag-hhi","tag-neoadjuvant-setting","tag-surgical-excision","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-02 00:26:49","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":555256,"slug":"atteindre-lobjectif-grace-a-des-strategies-therapeutiques-innovantes","post_title":"Atteindre l'objectif gr\u00e2ce \u00e0 des strat\u00e9gies th\u00e9rapeutiques innovantes","href":"https:\/\/medizinonline.com\/fr\/atteindre-lobjectif-grace-a-des-strategies-therapeutiques-innovantes\/"},"it_IT":{"locale":"it_IT","id":555253,"slug":"raggiungere-lobiettivo-con-strategie-terapeutiche-innovative","post_title":"Raggiungere l'obiettivo con strategie terapeutiche innovative","href":"https:\/\/medizinonline.com\/it\/raggiungere-lobiettivo-con-strategie-terapeutiche-innovative\/"},"pt_PT":{"locale":"pt_PT","id":555250,"slug":"atingir-o-objetivo-com-estrategias-terapeuticas-inovadoras","post_title":"Atingir o objetivo com estrat\u00e9gias terap\u00eauticas inovadoras","href":"https:\/\/medizinonline.com\/pt-pt\/atingir-o-objetivo-com-estrategias-terapeuticas-inovadoras\/"},"es_ES":{"locale":"es_ES","id":555307,"slug":"alcanzar-la-meta-con-estrategias-terapeuticas-innovadoras","post_title":"Alcanzar la meta con estrategias terap\u00e9uticas innovadoras","href":"https:\/\/medizinonline.com\/es\/alcanzar-la-meta-con-estrategias-terapeuticas-innovadoras\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/555259","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=555259"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/555259\/revisions"}],"predecessor-version":[{"id":555261,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/555259\/revisions\/555261"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/555260"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=555259"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=555259"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=555259"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=555259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}