{"id":556639,"date":"2026-06-10T12:30:00","date_gmt":"2026-06-10T10:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=556639"},"modified":"2026-06-10T14:30:34","modified_gmt":"2026-06-10T12:30:34","slug":"modern-molecular-diagnostics-and-targeted-therapy-options","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/modern-molecular-diagnostics-and-targeted-therapy-options\/","title":{"rendered":"Modern molecular diagnostics and targeted therapy options"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are increasingly opening up personalized treatment options. <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmodern-molecular-diagnostics-and-targeted-therapy-options%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmodern-molecular-diagnostics-and-targeted-therapy-options%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":556640,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Cholangiocarcinoma  ","footnotes":""},"category":[11548,11508,11391,11370,11503],"tags":[92306,92316,25796,92332,92325,92317,92333,92319,92308,92313,92309,92305,92310,92315,92322,92327,92304,92314,92307,92312,92321,92334,33663,92328,92303,92330,92318,92324,15767,92311,92331,92336,11767,92329,92320,92335,92326,92323],"powerkit_post_featured":[],"class_list":["post-556639","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-education","category-gastroenterology-and-hepatology","category-oncology","category-studies","tag-approved-fgfr-inhibitors-pemigatinib-and-futibatinib","tag-braf-v600e","tag-cholangiocarcinoma","tag-clinical-studies-cholangiocarcinoma","tag-combination-of-dabrafenib-and-trametinib","tag-dabrafenib-trametinib","tag-dmmr","tag-entrectinib","tag-extrahepatic-cholangiocarcinoma","tag-fgfr-inhibitors","tag-fgfr2-fusion","tag-fight-202-study","tag-foenix-cca2-study","tag-futibatinib","tag-her2-amplification","tag-her2-positive-extrahepatic-cca","tag-her2-targeted-therapy","tag-idh1-mutation","tag-intrahepatic-cholangiocarcinoma","tag-ivosidenib-effective-second-line-therapy","tag-larotrectinib","tag-molecular-alterations","tag-molecular-diagnostics-en","tag-msi-h","tag-next-generation-sequencing","tag-ngs-profiling","tag-ntrk-merger","tag-ntrk-mergers","tag-pembrolizumab-en","tag-pemigatinib-in-previously-treated-patients-with-fgfr2-fusions","tag-personalized-oncology","tag-prognosis-and-therapy","tag-targeted-therapy","tag-trastuzumab-based-combinations","tag-trk-inhibitors","tag-tumor-board-switzerland","tag-tumor-agnostic-therapies-such-as-larotrectinib-or-entrectinib","tag-tumors-with-braf-v600e-mutations","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-15 08:55:03","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":556755,"slug":"diagnostics-moleculaires-modernes-et-options-therapeutiques-ciblees","post_title":"Diagnostics mol\u00e9culaires modernes et options th\u00e9rapeutiques cibl\u00e9es","href":"https:\/\/medizinonline.com\/fr\/diagnostics-moleculaires-modernes-et-options-therapeutiques-ciblees\/"},"it_IT":{"locale":"it_IT","id":556752,"slug":"la-moderna-diagnostica-molecolare-e-le-opzioni-di-terapia-mirata","post_title":"La moderna diagnostica molecolare e le opzioni di terapia mirata","href":"https:\/\/medizinonline.com\/it\/la-moderna-diagnostica-molecolare-e-le-opzioni-di-terapia-mirata\/"},"pt_PT":{"locale":"pt_PT","id":556717,"slug":"diagnosticos-moleculares-modernos-e-opcoes-de-terapia-direcionada","post_title":"Diagn\u00f3sticos moleculares modernos e op\u00e7\u00f5es de terapia direcionada","href":"https:\/\/medizinonline.com\/pt-pt\/diagnosticos-moleculares-modernos-e-opcoes-de-terapia-direcionada\/"},"es_ES":{"locale":"es_ES","id":556713,"slug":"diagnosticos-moleculares-modernos-y-opciones-de-terapia-dirigida","post_title":"Diagn\u00f3sticos moleculares modernos y opciones de terapia dirigida","href":"https:\/\/medizinonline.com\/es\/diagnosticos-moleculares-modernos-y-opciones-de-terapia-dirigida\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=556639"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556639\/revisions"}],"predecessor-version":[{"id":556641,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556639\/revisions\/556641"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/556640"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=556639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=556639"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=556639"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=556639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}