{"id":556675,"date":"2026-05-20T00:30:00","date_gmt":"2026-05-19T22:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=556675"},"modified":"2026-05-20T08:24:53","modified_gmt":"2026-05-20T06:24:53","slug":"fertility-preservation-from-gonads-to-genomes-to-genoids","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/fertility-preservation-from-gonads-to-genomes-to-genoids\/","title":{"rendered":"Fertility preservation from gonads to genomes to genoids"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Ovarian and prostate cancers rely on common hormonal, genetic and inflammatory mechanisms that influence both tumor progression and gonadal reproductive function in both sexes; in addition, ovarian stem cell populations identified by the Tilly lab show that adult germ cell niches have regenerative potentials whose activity is functionally impaired by aging, inflammation and metabolic stress. The text makes it clear that the same endocrine and epigenetic networks that characterize PCOS, endometriosis and male fertility disorders also control the pathogenesis of hormone-dependent tumors and thus open up new starting points for prevention, fertility preservation and personalized therapies. <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Ffertility-preservation-from-gonads-to-genomes-to-genoids%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Ovarian and prostate cancers rely on common hormonal, genetic and inflammatory mechanisms that influence both tumor progression and gonadal reproductive function in both sexes; in addition, ovarian stem cell populations&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Ffertility-preservation-from-gonads-to-genomes-to-genoids%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":556676,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Prostate and ovarian cancer","footnotes":""},"category":[11548,22615,11400,11370,11503,11490],"tags":[92554,18076,17927,92553,92555],"powerkit_post_featured":[],"class_list":["post-556675","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-cme-continuing-education","category-gynecology","category-oncology","category-studies","category-urology","tag-genoids","tag-ovarian-cancer","tag-prostate-cancer","tag-reproductive-resilience","tag-reprogramming","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-22 20:24:11","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":556672,"slug":"preservation-de-la-fertilite-des-gonades-aux-genomes-en-passant-par-les-genoides","post_title":"Pr\u00e9servation de la fertilit\u00e9, des gonades aux g\u00e9nomes en passant par les g\u00e9no\u00efdes","href":"https:\/\/medizinonline.com\/fr\/preservation-de-la-fertilite-des-gonades-aux-genomes-en-passant-par-les-genoides\/"},"it_IT":{"locale":"it_IT","id":556669,"slug":"conservazione-della-fertilita-dalle-gonadi-ai-genomi-ai-genoidi","post_title":"Conservazione della fertilit\u00e0 dalle gonadi ai genomi ai genoidi","href":"https:\/\/medizinonline.com\/it\/conservazione-della-fertilita-dalle-gonadi-ai-genomi-ai-genoidi\/"},"pt_PT":{"locale":"pt_PT","id":556666,"slug":"preservacao-da-fertilidade-das-gonadas-aos-genomas-e-aos-genoides","post_title":"Preserva\u00e7\u00e3o da fertilidade: das g\u00f3nadas aos genomas e aos genoides","href":"https:\/\/medizinonline.com\/pt-pt\/preservacao-da-fertilidade-das-gonadas-aos-genomas-e-aos-genoides\/"},"es_ES":{"locale":"es_ES","id":556663,"slug":"preservacion-de-la-fertilidad-de-las-gonadas-a-los-genomas-y-a-los-genoides","post_title":"Preservaci\u00f3n de la fertilidad de las g\u00f3nadas a los genomas y a los genoides","href":"https:\/\/medizinonline.com\/es\/preservacion-de-la-fertilidad-de-las-gonadas-a-los-genomas-y-a-los-genoides\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=556675"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556675\/revisions"}],"predecessor-version":[{"id":556677,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/556675\/revisions\/556677"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/556676"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=556675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=556675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=556675"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=556675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}