{"id":558665,"date":"2026-06-10T22:00:00","date_gmt":"2026-06-10T20:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/pharmacotherapies-as-game-changers-what-are-the-upcoming-challenges\/"},"modified":"2026-06-17T10:59:15","modified_gmt":"2026-06-17T08:59:15","slug":"pharmacotherapies-as-game-changers-what-are-the-upcoming-challenges","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/pharmacotherapies-as-game-changers-what-are-the-upcoming-challenges\/","title":{"rendered":"Pharmacotherapies as \u201cGame Changers\u201d\u2014What Are the Upcoming Challenges?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Two drug therapy options\u2014semaglutide (s.c.) and resmetirom (oral)\u2014are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a long time, no drug therapies specifically approved for the indication of steatotic liver disease were available. The ESSENCE and MAESTRO-NASH studies were pivotal. In addition, an ESSENCE and MAESTRO-NASH study on survodutide is currently underway, and many other clinical trials are planned or already in progress. During a panel discussion, international experts discussed the key challenges and goals of current research efforts.    <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fpharmacotherapies-as-game-changers-what-are-the-upcoming-challenges%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Two drug therapy options\u2014semaglutide (s.c.) and resmetirom (oral)\u2014are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fpharmacotherapies-as-game-changers-what-are-the-upcoming-challenges%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":558668,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"MASH","footnotes":""},"category":[11548,11513,11384,11391,11297,11503],"tags":[94639,94640,83694,77506,94635,11780,51750,77508,17444,82940,91393,94637],"powerkit_post_featured":[],"class_list":["post-558665","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-congress-reports","category-endocrinology-and-diabetology","category-gastroenterology-and-hepatology","category-general-internal-medicine","category-studies","tag-essence","tag-maestro-nash","tag-mash-en-3","tag-masld-en","tag-metabolic-dysfunction-associated-steatohepatitis-2","tag-pharmacotherapy","tag-phase-iii-en","tag-resmetirom-en","tag-semaglutide-en-2","tag-steatohepatitis-en","tag-steatotic-liver-diseases-2","tag-survodutide","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-03 03:07:42","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":558429,"slug":"les-pharmacotherapies-un-tournant-decisif-quels-sont-les-defis-a-venir-2","post_title":"Les pharmacoth\u00e9rapies, un v\u00e9ritable \u00ab tournant \u00bb : quels sont les d\u00e9fis \u00e0 venir ?","href":"https:\/\/medizinonline.com\/fr\/les-pharmacotherapies-un-tournant-decisif-quels-sont-les-defis-a-venir-2\/"},"it_IT":{"locale":"it_IT","id":558676,"slug":"le-farmacoterapie-come-game-changer-quali-sono-le-sfide-future","post_title":"Le farmacoterapie come \u00abgame changer\u00bb: quali sono le sfide future?","href":"https:\/\/medizinonline.com\/it\/le-farmacoterapie-come-game-changer-quali-sono-le-sfide-future\/"},"pt_PT":{"locale":"pt_PT","id":558682,"slug":"as-farmacoterapias-como-fator-de-mudanca-quais-sao-os-desafios-que-se-avizinham","post_title":"As farmacoterapias como \u00abfator de mudan\u00e7a\u00bb \u2013 quais s\u00e3o os desafios que se avizinham?","href":"https:\/\/medizinonline.com\/pt-pt\/as-farmacoterapias-como-fator-de-mudanca-quais-sao-os-desafios-que-se-avizinham\/"},"es_ES":{"locale":"es_ES","id":558731,"slug":"las-farmacoterapias-como-punto-de-inflexion-cuales-son-los-retos-que-se-avecinan","post_title":"Las farmacoterapias como \u00abpunto de inflexi\u00f3n\u00bb: \u00bfcu\u00e1les son los retos que se avecinan?","href":"https:\/\/medizinonline.com\/es\/las-farmacoterapias-como-punto-de-inflexion-cuales-son-los-retos-que-se-avecinan\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/558665","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=558665"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/558665\/revisions"}],"predecessor-version":[{"id":558669,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/558665\/revisions\/558669"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/558668"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=558665"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=558665"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=558665"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=558665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}