{"id":559942,"date":"2026-08-04T22:52:09","date_gmt":"2026-08-04T20:52:09","guid":{"rendered":"https:\/\/medizinonline.com\/?p=559942"},"modified":"2026-08-04T22:52:21","modified_gmt":"2026-08-04T20:52:21","slug":"first-aldosterone-synthase-inhibitor-is-here","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/first-aldosterone-synthase-inhibitor-is-here\/","title":{"rendered":"First Aldosterone Synthase Inhibitor Is Here"},"content":{"rendered":"\n

It is the first new class of antihypertensive drugs in years: On May 18, 2026, the U.S. Food and Drug Administration (FDA) approved Baxdrostat (Baxfendy) as the first and only aldosterone synthase inhibitor for the treatment of hypertension. The drug targets a root cause of difficult-to-control hypertension\u2014excessive aldosterone production\u2014and lowers blood pressure in areas where established treatments often reach their limits. The approval is supported by the Phase III BaxHTN study, complemented by the Bax24 study on 24-hour blood pressure monitoring in resistant hypertension. With lorundrostat as the second aldosterone synthase inhibitor and zilebesiran as an RNA-based approach, a whole wave of new therapeutic principles is also emerging. <\/strong><\/p>\n\n

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It is the first new class of antihypertensive drugs in years: On May 18, 2026, the U.S. Food and Drug Administration (FDA) approved Baxdrostat (Baxfendy) as the first and only……... <\/p>\n

Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich
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Already a member? Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":559945,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Baxdrostat \u2013 a new class of drugs for treating difficult-to-control hypertension","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11548,11359,11508,11297,11442,11503],"tags":[95165,95164,13446],"powerkit_post_featured":[],"class_list":["post-559942","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-cardiology","category-education","category-general-internal-medicine","category-pharmacology-and-toxicology","category-studies","tag-aldosterone-synthase-inhibitors","tag-baxdrostat","tag-hypertension-en-2","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-08-21 20:28:36","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":560781,"slug":"le-premier-inhibiteur-de-laldosterone-synthase-est-desormais-disponible","post_title":"Le premier inhibiteur de l'aldost\u00e9rone synthase est d\u00e9sormais disponible","href":"https:\/\/medizinonline.com\/fr\/le-premier-inhibiteur-de-laldosterone-synthase-est-desormais-disponible\/"},"it_IT":{"locale":"it_IT","id":560784,"slug":"e-disponibile-il-primo-inibitore-dellaldosterone-sintasi","post_title":"\u00c8 disponibile il primo inibitore dell'aldosterone sintasi","href":"https:\/\/medizinonline.com\/it\/e-disponibile-il-primo-inibitore-dellaldosterone-sintasi\/"},"pt_PT":{"locale":"pt_PT","id":560787,"slug":"chegou-o-primeiro-inibidor-da-aldosterona-sintase","post_title":"Chegou o primeiro inibidor da aldosterona sintase","href":"https:\/\/medizinonline.com\/pt-pt\/chegou-o-primeiro-inibidor-da-aldosterona-sintase\/"},"es_ES":{"locale":"es_ES","id":560790,"slug":"ya-esta-disponible-el-primer-inhibidor-de-la-aldosterona-sintasa","post_title":"Ya est\u00e1 disponible el primer inhibidor de la aldosterona sintasa","href":"https:\/\/medizinonline.com\/es\/ya-esta-disponible-el-primer-inhibidor-de-la-aldosterona-sintasa\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/559942","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=559942"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/559942\/revisions"}],"predecessor-version":[{"id":559948,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/559942\/revisions\/559948"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/559945"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=559942"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=559942"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=559942"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=559942"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}