{"id":561271,"date":"2026-07-25T12:30:00","date_gmt":"2026-07-25T10:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=561271"},"modified":"2026-07-25T12:40:13","modified_gmt":"2026-07-25T10:40:13","slug":"mutations-and-molecular-diagnostics-in-treatment-decisions","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/mutations-and-molecular-diagnostics-in-treatment-decisions\/","title":{"rendered":"Mutations and Molecular Diagnostics in Treatment Decisions"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Primary myelofibrosis (PMF) is a rare, biologically complex myeloproliferative neoplasm whose course is strongly influenced by molecular, epigenetic, and immunological factors. Advances in genomics, spatial transcriptomics, and targeted therapies have fundamentally transformed diagnosis and treatment in recent years and are increasingly enabling more precise, personalized treatment decisions. <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmutations-and-molecular-diagnostics-in-treatment-decisions%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Primary myelofibrosis (PMF) is a rare, biologically complex myeloproliferative neoplasm whose course is strongly influenced by molecular, epigenetic, and immunological factors. Advances in genomics, spatial transcriptomics, and targeted therapies have&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fmutations-and-molecular-diagnostics-in-treatment-decisions%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":561286,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Myelofibrosis  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