{"id":565958,"date":"2026-09-10T02:00:00","date_gmt":"2026-09-10T00:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/what-are-the-most-important-game-changers\/"},"modified":"2026-09-16T22:48:49","modified_gmt":"2026-09-16T20:48:49","slug":"what-are-the-most-important-game-changers","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/what-are-the-most-important-game-changers\/","title":{"rendered":"What are the most important game-changers?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>IgA nephropathy, also known as \u201cBerger\u2019s disease,\u201d is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney biopsy. Advances in research into the pathophysiological mechanisms have led to the development of innovative treatment strategies, for which some Phase IIIdata\u2014including fusion proteins targeting the cytokines BAFF and\/or APRIL, as well as selective endothelin A receptor antagonists and complement inhibitors. Furthermore, there is also interesting news regarding treatment options for IgAN that have also cleared regulatory hurdles in Europe.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhat-are-the-most-important-game-changers%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>IgA nephropathy, also known as \u201cBerger\u2019s disease,\u201d is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fwhat-are-the-most-important-game-changers%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":565962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"IgA Nephropathy: The Evolving Landscape of Treatment  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