{"id":566462,"date":"2026-09-12T03:00:00","date_gmt":"2026-09-12T01:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/long-term-data-from-the-crown-study-efficacy-and-intracranial-control\/"},"modified":"2026-09-17T21:52:25","modified_gmt":"2026-09-17T19:52:25","slug":"long-term-data-from-the-crown-study-efficacy-and-intracranial-control","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/long-term-data-from-the-crown-study-efficacy-and-intracranial-control\/","title":{"rendered":"Long-term data from the CROWN study: Efficacy and intracranial control"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Updated 7-year data from the CROWN study were presented at the 2026 ASCO Annual Meeting. These data confirm stable long-term disease control with lorlatinib and reinforce its role as a first-line treatment for ALK-positive NSCLC. The results show that progression-free survival has not yet been reached and that intracranial disease control is maintained over the long term.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Flong-term-data-from-the-crown-study-efficacy-and-intracranial-control%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Updated 7-year data from the CROWN study were presented at the 2026 ASCO Annual Meeting. These data confirm stable long-term disease control with lorlatinib and reinforce its role as a&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Flong-term-data-from-the-crown-study-efficacy-and-intracranial-control%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":566463,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Non-small-cell lung cancer (NSCLC)","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11548,11513,11370,11455,11503],"tags":[],"powerkit_post_featured":[],"class_list":["post-566462","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-congress-reports","category-oncology","category-pneumology","category-studies","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-09-24 23:29:35","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":566465,"slug":"donnees-a-long-terme-de-letude-crown-efficacite-et-controle-intracranien","post_title":"Donn\u00e9es \u00e0 long terme de l'\u00e9tude CROWN : efficacit\u00e9 et contr\u00f4le intracr\u00e2nien","href":"https:\/\/medizinonline.com\/fr\/donnees-a-long-terme-de-letude-crown-efficacite-et-controle-intracranien\/"},"it_IT":{"locale":"it_IT","id":566469,"slug":"dati-a-lungo-termine-dello-studio-crown-efficacia-e-controllo-intracranico","post_title":"Dati a lungo termine dello studio CROWN: efficacia e controllo intracranico","href":"https:\/\/medizinonline.com\/it\/dati-a-lungo-termine-dello-studio-crown-efficacia-e-controllo-intracranico\/"},"pt_PT":{"locale":"pt_PT","id":566476,"slug":"dados-a-longo-prazo-do-estudo-crown-eficacia-e-controlo-intracraniano","post_title":"Dados a longo prazo do estudo CROWN: efic\u00e1cia e controlo intracraniano","href":"https:\/\/medizinonline.com\/pt-pt\/dados-a-longo-prazo-do-estudo-crown-eficacia-e-controlo-intracraniano\/"},"es_ES":{"locale":"es_ES","id":566483,"slug":"datos-a-largo-plazo-del-estudio-crown-eficacia-y-control-intracraneal","post_title":"Datos a largo plazo del estudio CROWN: eficacia y control intracraneal","href":"https:\/\/medizinonline.com\/es\/datos-a-largo-plazo-del-estudio-crown-eficacia-y-control-intracraneal\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/566462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=566462"}],"version-history":[{"count":3,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/566462\/revisions"}],"predecessor-version":[{"id":566609,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/566462\/revisions\/566609"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/566463"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=566462"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=566462"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=566462"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=566462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}