{"id":568505,"date":"2026-09-15T01:00:00","date_gmt":"2026-09-14T23:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/ovarian-cancer-why-a-small-cell-pool-determines-whether-the-cancer-recurs\/"},"modified":"2026-09-23T17:29:21","modified_gmt":"2026-09-23T15:29:21","slug":"ovarian-cancer-why-a-small-cell-pool-determines-whether-the-cancer-recurs","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/en\/ovarian-cancer-why-a-small-cell-pool-determines-whether-the-cancer-recurs\/","title":{"rendered":"Ovarian Cancer: Why a Small Cell Pool Determines Whether the Cancer Recurs"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Ovarian cancer is the deadliest gynecological malignancy, and the reason for this lies less in the initial response to treatment than in the almost universal recurrence. A recent review from Hong Kong summarizes what is known about ovarian tumor stem cells\u2014that rare and highly plastic subpopulation believed to be responsible for tumor initiation, peritoneal seeding, chemoresistance, and recurrence. The study is also worth reading because it explicitly identifies the limitations of the concept: The commonly used markers are enrichment tools rather than proof of identity, and clinical trials to date on stem cell-targeted agents have largely yielded negative results.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fovarian-cancer-why-a-small-cell-pool-determines-whether-the-cancer-recurs%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Ovarian cancer is the deadliest gynecological malignancy, and the reason for this lies less in the initial response to treatment than in the almost universal recurrence. A recent review from&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/en\/my-account\/packages\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/en\/log-in\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fen%2Fovarian-cancer-why-a-small-cell-pool-determines-whether-the-cancer-recurs%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":568507,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Gynecological oncology","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11548,11508,11396,11400,11370,11503],"tags":[18076,20340],"powerkit_post_featured":[],"class_list":["post-568505","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-en","category-education","category-genetics","category-gynecology","category-oncology","category-studies","tag-ovarian-cancer","tag-ovarian-cancer-en","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-01 03:04:49","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"en_US","wpml_translations":{"fr_FR":{"locale":"fr_FR","id":568511,"slug":"cancer-de-lovaire-pourquoi-un-petit-reservoir-de-cellules-est-determinant-pour-la-recidive","post_title":"Cancer de l'ovaire : pourquoi un petit r\u00e9servoir de cellules est d\u00e9terminant pour la r\u00e9cidive","href":"https:\/\/medizinonline.com\/fr\/cancer-de-lovaire-pourquoi-un-petit-reservoir-de-cellules-est-determinant-pour-la-recidive\/"},"it_IT":{"locale":"it_IT","id":568440,"slug":"carcinoma-ovarico-perche-un-piccolo-pool-cellulare-e-determinante-per-la-recidiva","post_title":"Carcinoma ovarico: perch\u00e9 un piccolo pool cellulare \u00e8 determinante per la recidiva","href":"https:\/\/medizinonline.com\/it\/carcinoma-ovarico-perche-un-piccolo-pool-cellulare-e-determinante-per-la-recidiva\/"},"pt_PT":{"locale":"pt_PT","id":568443,"slug":"cancro-do-ovario-por-que-razao-um-pequeno-conjunto-de-celulas-e-determinante-para-a-recidiva","post_title":"Cancro do ov\u00e1rio: por que raz\u00e3o um pequeno conjunto de c\u00e9lulas \u00e9 determinante para a recidiva","href":"https:\/\/medizinonline.com\/pt-pt\/cancro-do-ovario-por-que-razao-um-pequeno-conjunto-de-celulas-e-determinante-para-a-recidiva\/"},"es_ES":{"locale":"es_ES","id":568446,"slug":"cancer-de-ovario-por-que-un-pequeno-conjunto-de-celulas-es-determinante-para-la-recidiva","post_title":"C\u00e1ncer de ovario: por qu\u00e9 un peque\u00f1o conjunto de c\u00e9lulas es determinante para la recidiva","href":"https:\/\/medizinonline.com\/es\/cancer-de-ovario-por-que-un-pequeno-conjunto-de-celulas-es-determinante-para-la-recidiva\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/568505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/comments?post=568505"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/568505\/revisions"}],"predecessor-version":[{"id":568509,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/posts\/568505\/revisions\/568509"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media\/568507"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/media?parent=568505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/category?post=568505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/tags?post=568505"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/en\/wp-json\/wp\/v2\/powerkit_post_featured?post=568505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}