{"id":567060,"date":"2026-10-09T12:30:00","date_gmt":"2026-10-09T10:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=567060"},"modified":"2026-09-21T11:25:36","modified_gmt":"2026-09-21T09:25:36","slug":"sglt2i-metformina-o-ambas","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/es\/sglt2i-metformina-o-ambas\/","title":{"rendered":"\u00bfSGLT2i, metformina o ambas?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>La metformina sigue siendo el tratamiento farmacol\u00f3gico de primera l\u00ednea para la diabetes tipo 2 reci\u00e9n diagnosticada, mientras que los inhibidores del cotransportador de sodio-glucosa tipo 2(SGLT2) est\u00e1n indicados en presencia de una enfermedad cardiovascular o renal establecida, o de un alto riesgo cardiovascular. Se ha estudiado si el tratamiento con un inhibidor de SGLT2 en una fase temprana modifica la funci\u00f3n y la estructura vasculares en personas que no han recibido tratamiento previo y a las que se les ha diagnosticado recientemente la diabetes tipo 2, mediante la comparaci\u00f3n entre la dapagliflozina en monoterapia, la metformina en monoterapia y la combinaci\u00f3n de ambas.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/es\/mi-cuenta\/paquetes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">\u00bfYa eres miembro? <a href=\"https:\/\/medizinonline.com\/es\/conectarse\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fes%2Fsglt2i-metformina-o-ambas%2F\">Accede aqu\u00ed<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>La metformina sigue siendo el tratamiento farmacol\u00f3gico de primera l\u00ednea para la diabetes tipo 2 reci\u00e9n diagnosticada, mientras que los inhibidores del cotransportador de sodio-glucosa tipo 2(SGLT2) est\u00e1n indicados en&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/es\/mi-cuenta\/paquetes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">\u00bfYa eres miembro? <a href=\"https:\/\/medizinonline.com\/es\/conectarse\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fes%2Fsglt2i-metformina-o-ambas%2F\">Accede aqu\u00ed<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":567063,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Tratamiento de primera l\u00ednea para la diabetes tipo 2","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11552,11352,11475,11478],"tags":[23317,12033,102221,33376,11666,19514,86756,80013,11941],"powerkit_post_featured":[],"class_list":["post-567060","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-es","category-endocrinologia-y-diabetologia","category-estudios","category-formacion-continua","tag-dapagliflozina","tag-diabetes-tipo-2-es-2","tag-espesor-de-la-capa-intima-media-de-la-carotida","tag-inhibidores-sglt2-es","tag-metformina","tag-riesgo-cardiovascular","tag-sglt2i","tag-t2d-es","tag-terapia-de-primera-linea","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-16 14:39:40","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"es_ES","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/posts\/567060","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/comments?post=567060"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/posts\/567060\/revisions"}],"predecessor-version":[{"id":568100,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/posts\/567060\/revisions\/568100"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/media\/567063"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/media?parent=567060"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/category?post=567060"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/tags?post=567060"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/es\/wp-json\/wp\/v2\/powerkit_post_featured?post=567060"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}