Entretien avec le professeur Dr Kucher.<\/p>\n
<\/p>\n
Prof. Kucher, qu’est-ce qui a motiv\u00e9 le d\u00e9veloppement de la thrombolyse assist\u00e9e par ultrasons ?<\/strong><\/p>\n Quel est l’effet des ondes ultrasonores sur l’embole ?<\/strong><\/p>\n Comme nous le savons, les ultrasons seuls ne peuvent pas dissoudre le thrombus. L’effet m\u00e9canique des ondes ultrasonores entra\u00eene d’une part la d\u00e9stabilisation du thrombus avec amincissement des filaments de fibrine. En m\u00eame temps, le m\u00e9dicament est press\u00e9 dans le thrombus en raison du “streaming acoustique”, ce qui entra\u00eene une dissolution plus rapide, m\u00eame \u00e0 faible dose.<\/p>\n Les r\u00e9sultats de l’\u00e9tude de phase II sont prometteurs. Quelle est l’\u00e9volution de la thrombolyse assist\u00e9e par ultrasons ?<\/strong><\/p>\n Des \u00e9tudes futures permettront de v\u00e9rifier si la lyse par cath\u00e9ter est plus s\u00fbre que la lyse syst\u00e9mique, notamment en ce qui concerne la r\u00e9duction des h\u00e9morragies graves.<\/p>\n Entretien : Regina Scharf<\/strong><\/em><\/p>\n","protected":false},"excerpt":{"rendered":" Entretien avec le professeur Dr Kucher.<\/p>\n","protected":false},"author":4,"featured_media":35997,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Interview","footnotes":""},"category":[11378,11539,11477,11549],"tags":[61129,61127,61120,12901],"powerkit_post_featured":[],"class_list":["post-347084","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cardiologie","category-interviews-fr","category-pneumologie-fr","category-rx-fr","tag-embolus-fr","tag-etude-ultima","tag-nils-kucher-fr","tag-thrombolyse-fr","pmpro-has-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-01 15:42:58","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"fr_FR","wpml_translations":{"it_IT":{"locale":"it_IT","id":347095,"slug":"intervista-con-il-prof-dr-med-nils-kucher-berna-responsabile-dello-studio-ultima","post_title":"Intervista con il Prof. Dr. med. Nils Kucher, Berna, responsabile dello studio ULTIMA","href":"https:\/\/medizinonline.com\/it\/intervista-con-il-prof-dr-med-nils-kucher-berna-responsabile-dello-studio-ultima\/"},"pt_PT":{"locale":"pt_PT","id":347104,"slug":"entrevista-com-o-prof-dr-med-nils-kucher-bern-chefe-do-estudo-ultima","post_title":"Entrevista com o Prof. Dr. med. Nils Kucher, Bern, chefe do estudo ULTIMA","href":"https:\/\/medizinonline.com\/pt-pt\/entrevista-com-o-prof-dr-med-nils-kucher-bern-chefe-do-estudo-ultima\/"},"es_ES":{"locale":"es_ES","id":347108,"slug":"entrevista-con-el-prof-dr-med-nils-kucher-berna-director-del-estudio-ultima","post_title":"Entrevista con el Prof. Dr. med. Nils Kucher, Berna, director del estudio ULTIMA","href":"https:\/\/medizinonline.com\/es\/entrevista-con-el-prof-dr-med-nils-kucher-berna-director-del-estudio-ultima\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/347084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/comments?post=347084"}],"version-history":[{"count":0,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/347084\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media\/35997"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media?parent=347084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/category?post=347084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/tags?post=347084"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/powerkit_post_featured?post=347084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n Prof. Dr Kucher : <\/em>
\n<\/strong>Des registres \u00e0 grande \u00e9chelle ont confirm\u00e9 qu’environ deux tiers des patients souffrant d’embolie pulmonaire massive ne re\u00e7oivent pas de thrombolyse potentiellement salvatrice en raison du risque d’h\u00e9morragie. D’autre part, nous observons parfois que des patients initialement stables et trait\u00e9s selon les normes d\u00e9c\u00e8dent des suites d’une embolie pulmonaire. Une meilleure th\u00e9rapie est \u00e9galement n\u00e9cessaire car de nombreuses personnes souffrent des sympt\u00f4mes d’une charge cardiaque droite pendant des mois. Enfin, le traitement doit permettre d’\u00e9viter des cons\u00e9quences tardives importantes comme la chronicisation d’une hypertension pulmonaire.<\/p>\n