{"id":401312,"date":"2025-05-12T10:00:00","date_gmt":"2025-05-12T08:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/maladie-de-crohn-traitement-step-up-ou-top-down\/"},"modified":"2025-06-11T14:23:26","modified_gmt":"2025-06-11T12:23:26","slug":"maladie-de-crohn-traitement-step-up-ou-top-down","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/maladie-de-crohn-traitement-step-up-ou-top-down\/","title":{"rendered":"Maladie de Crohn : traitement &#8220;step-up&#8221; ou &#8220;top-down&#8221; ?"},"content":{"rendered":"\n<p><strong>Actuellement, il n&#8217;existe pas de param\u00e8tres clairement d\u00e9finis pour le contr\u00f4le du traitement, comme le constate la mise \u00e0 jour du guide S3 sur le diagnostic et le traitement de la maladie de Crohn, publi\u00e9e l&#8217;ann\u00e9e derni\u00e8re. Il s&#8217;agit l\u00e0 d&#8217;un dilemme qui soul\u00e8ve la question d&#8217;autres indicateurs pour \u00e9valuer l&#8217;\u00e9volution du traitement. Dans l&#8217;\u00e9tude PROFILE, une strat\u00e9gie th\u00e9rapeutique avec utilisation pr\u00e9coce d&#8217;un m\u00e9dicament biologique s&#8217;est av\u00e9r\u00e9e sup\u00e9rieure \u00e0 la proc\u00e9dure standard en termes de r\u00e9mission sans st\u00e9ro\u00efdes et sans chirurgie.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/fr\/mon-compte\/paquets\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/fr\/se-connecter\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Ffr%2Fmaladie-de-crohn-traitement-step-up-ou-top-down%2F\">Connectez-vous ici<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Actuellement, il n&#8217;existe pas de param\u00e8tres clairement d\u00e9finis pour le contr\u00f4le du traitement, comme le constate la mise \u00e0 jour du guide S3 sur le diagnostic et le traitement de&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/fr\/mon-compte\/paquets\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/fr\/se-connecter\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Ffr%2Fmaladie-de-crohn-traitement-step-up-ou-top-down%2F\">Connectez-vous ici<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":401316,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Maladies inflammatoires chroniques de l'intestin (MICI)  ","footnotes":""},"category":[11527,11414,11315,11535,11549],"tags":[16021,67165,37068,15758,83031,12573,83032],"powerkit_post_featured":[],"class_list":["post-401312","post","type-post","status-publish","format-standard","has-post-thumbnail","category-etudes","category-gastro-enterologie-et-hepatologie","category-medecine-interne-generale","category-rapports-de-congres","category-rx-fr","tag-ced-fr","tag-chronisch-entzuendliche-darmerkrankungen-2-fr","tag-m-crohn-fr","tag-maladie-de-crohn","tag-step-up-fr","tag-therapie-fr","tag-top-down-fr","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-26 00:09:31","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"fr_FR","wpml_translations":{"it_IT":{"locale":"it_IT","id":401327,"slug":"malattia-di-crohn-terapia-step-up-o-top-down","post_title":"Malattia di Crohn: terapia step-up o top-down?","href":"https:\/\/medizinonline.com\/it\/malattia-di-crohn-terapia-step-up-o-top-down\/"},"pt_PT":{"locale":"pt_PT","id":401322,"slug":"doenca-de-crohn-terapia-intensiva-ou-descendente","post_title":"Doen\u00e7a de Crohn: terapia intensiva ou descendente?","href":"https:\/\/medizinonline.com\/pt-pt\/doenca-de-crohn-terapia-intensiva-ou-descendente\/"},"es_ES":{"locale":"es_ES","id":401330,"slug":"enfermedad-de-crohn-terapia-ascendente-o-descendente","post_title":"Enfermedad de Crohn: \u00bfterapia ascendente o descendente?","href":"https:\/\/medizinonline.com\/es\/enfermedad-de-crohn-terapia-ascendente-o-descendente\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/401312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/comments?post=401312"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/401312\/revisions"}],"predecessor-version":[{"id":401317,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/401312\/revisions\/401317"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media\/401316"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media?parent=401312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/category?post=401312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/tags?post=401312"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/powerkit_post_featured?post=401312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}