{"id":459460,"date":"2025-12-31T13:30:00","date_gmt":"2025-12-31T12:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=459460"},"modified":"2025-12-31T14:36:54","modified_gmt":"2025-12-31T13:36:54","slug":"agonistes-des-recepteurs-du-glp-1-en-cardiologie","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/agonistes-des-recepteurs-du-glp-1-en-cardiologie\/","title":{"rendered":"Agonistes des r\u00e9cepteurs du GLP-1 en cardiologie"},"content":{"rendered":"\n

Les agonistes des r\u00e9cepteurs du GLP-1 (GLP-1RA) sont pass\u00e9s en peu de temps du statut de m\u00e9dicaments antidiab\u00e9tiques \u00e0 celui de th\u00e9rapies cardiom\u00e9taboliques avec une r\u00e9duction cliniquement prouv\u00e9e des crit\u00e8res cardiovasculaires s\u00e9v\u00e8res – et ce de plus en plus au-del\u00e0 de la population diab\u00e9tique classique. Les bases m\u00e9canistiques vont des effets anti-ath\u00e9rog\u00e8nes et endoth\u00e9liaux \u00e0 la r\u00e9duction substantielle du poids avec des modifications favorables de la pression art\u00e9rielle et des lipides, en passant par des m\u00e9canismes anti-inflammatoires et de protection cardiaque directe. L’article suivant pr\u00e9sente les bases physiologiques, classe de mani\u00e8re critique les preuves de r\u00e9sultats et aborde les substances sp\u00e9cifiques suivantes : liraglutide, semaglutide (s.c. et oral), dulaglutide, albiglutide, efpeglenatide, exenatide et lixisenatide. Les concepts d’incr\u00e9tines duales et triples sont esquiss\u00e9s en perspective. Enfin, nous aborderons la s\u00e9curit\u00e9, la mise en \u0153uvre et les questions ouvertes pour la pratique. <\/strong><\/p>\n\n

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Les agonistes des r\u00e9cepteurs du GLP-1 (GLP-1RA) sont pass\u00e9s en peu de temps du statut de m\u00e9dicaments antidiab\u00e9tiques \u00e0 celui de th\u00e9rapies cardiom\u00e9taboliques avec une r\u00e9duction cliniquement prouv\u00e9e des crit\u00e8res……... <\/p>\n

Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich
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