{"id":560723,"date":"2026-07-09T00:30:00","date_gmt":"2026-07-08T22:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/linflammation-en-tant-quobjectif-therapeutique-a-part-entiere\/"},"modified":"2026-07-10T17:44:54","modified_gmt":"2026-07-10T15:44:54","slug":"linflammation-en-tant-quobjectif-therapeutique-a-part-entiere","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/linflammation-en-tant-quobjectif-therapeutique-a-part-entiere\/","title":{"rendered":"L’inflammation en tant qu’objectif th\u00e9rapeutique \u00e0 part enti\u00e8re"},"content":{"rendered":"\n

Pendant des d\u00e9cennies, la pr\u00e9vention cardiovasculaire a essentiellement tourn\u00e9 autour du cholest\u00e9rol. Or, une part importante des patients subit des \u00e9v\u00e9nements cardiovasculaires malgr\u00e9 des taux de lipides parfaitement contr\u00f4l\u00e9s, ce qui t\u00e9moigne d\u2019un risque r\u00e9siduel de plus en plus souvent attribu\u00e9 \u00e0 l\u2019inflammation. L\u2019\u00e9tude ORFAN permet de visualiser l\u2019inflammation coronaire par tomodensitom\u00e9trie, l\u2019IL-6 et la CRP hautement sensible (hsCRP) s\u2019av\u00e8rent \u00eatre de puissants marqueurs pronostiques, et le concept de Paul Ridker concernant les patientes \u00abSMuRF-less but inflamed\u00bb montre que l\u2019inflammation constitue un facteur de risque m\u00eame en l\u2019absence de facteurs de risque classiques. Du d\u00e9pistage, le chemin m\u00e8ne \u00e0 l\u2019intervention \u2013 avec la colchicine comme premier principe actif anti-inflammatoire autoris\u00e9 et un blocage cibl\u00e9 des cytokines \u00e0 l\u2019horizon. <\/strong><\/p>\n\n

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Pendant des d\u00e9cennies, la pr\u00e9vention cardiovasculaire a essentiellement tourn\u00e9 autour du cholest\u00e9rol. Or, une part importante des patients subit des \u00e9v\u00e9nements cardiovasculaires malgr\u00e9 des taux de lipides parfaitement contr\u00f4l\u00e9s, ce……... <\/p>\n

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