{"id":560840,"date":"2026-07-04T02:00:00","date_gmt":"2026-07-04T00:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/traitements-oraux-a-base-de-glp-1-attain-1-et-oasis-4-la-prochaine-avancee-majeure\/"},"modified":"2026-07-10T17:58:36","modified_gmt":"2026-07-10T15:58:36","slug":"traitements-oraux-a-base-de-glp-1-attain-1-et-oasis-4-la-prochaine-avancee-majeure","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/traitements-oraux-a-base-de-glp-1-attain-1-et-oasis-4-la-prochaine-avancee-majeure\/","title":{"rendered":"Traitements oraux \u00e0 base de GLP-1 : ATTAIN-1 et OASIS-4 \u2013 la prochaine avanc\u00e9e majeure"},"content":{"rendered":"\n

Les agonistes injectables des r\u00e9cepteurs du GLP-1 et le tirz\u00e9patide, agoniste double GIP\/GLP-1, ont red\u00e9fini le traitement m\u00e9dicamenteux de l\u2019ob\u00e9sit\u00e9 et ont permis, lors d\u2019\u00e9tudes, d\u2019obtenir des pertes de poids de l\u2019ordre de 15 \u00e0 20 %. Pourtant, leur utilisation concr\u00e8te reste limit\u00e9e \u2013 en raison de l\u2019injection elle-m\u00eame, des co\u00fbts, des exigences en mati\u00e8re de cha\u00eene du froid, des p\u00e9nuries d\u2019approvisionnement et d\u2019une observance th\u00e9rapeutique souvent insatisfaisante. L\u2019Organisation mondiale de la sant\u00e9 a clairement mis en \u00e9vidence ce d\u00e9s\u00e9quilibre en 2025 : m\u00eame en cas d\u2019augmentation rapide de la production, moins de 10 % des personnes potentiellement \u00e9ligibles au traitement devraient effectivement avoir acc\u00e8s \u00e0 ces substances d\u2019ici 2030. Une option orale <\/em>efficace et facilement adaptable \u00e0 grande \u00e9chelle ne r\u00e9pond donc pas seulement \u00e0 une question de confort, mais comble \u00e9galement une lacune majeure en mati\u00e8re de prise en charge. <\/strong><\/p>\n\n

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Les agonistes injectables des r\u00e9cepteurs du GLP-1 et le tirz\u00e9patide, agoniste double GIP\/GLP-1, ont red\u00e9fini le traitement m\u00e9dicamenteux de l\u2019ob\u00e9sit\u00e9 et ont permis, lors d\u2019\u00e9tudes, d\u2019obtenir des pertes de poids……... <\/p>\n

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