{"id":560888,"date":"2026-06-29T20:00:00","date_gmt":"2026-06-29T18:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/le-palopegteriparatide-dans-le-traitement-de-lhypoparathyroidie-chronique\/"},"modified":"2026-07-10T18:05:03","modified_gmt":"2026-07-10T16:05:03","slug":"le-palopegteriparatide-dans-le-traitement-de-lhypoparathyroidie-chronique","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/le-palopegteriparatide-dans-le-traitement-de-lhypoparathyroidie-chronique\/","title":{"rendered":"Le palop\u00e9gteriparatide dans le traitement de l’hypoparathyro\u00efdie chronique"},"content":{"rendered":"\n

L’hypoparathyro\u00efdie chronique fait partie des rares maladies endocriniennes pour lesquelles aucun traitement hormonal substitutif ciblant la cause n’\u00e9tait disponible depuis des d\u00e9cennies. Ce n’\u00e9tait pas le d\u00e9ficit hormonal sous-jacent qui \u00e9tait trait\u00e9, mais sa cons\u00e9quence biochimique : l’hypocalc\u00e9mie. Avec l\u2019autorisation de mise sur le march\u00e9 du palopegteriparatide par Swissmedic le 9 d\u00e9cembre 2025, un traitement de substitution \u00e0 base de parathormone (PTH) est d\u00e9sormais disponible pour la premi\u00e8re fois en Suisse \u00e0 l\u2019intention des patients adultes atteints de cette maladie. Au-del\u00e0 de la stabilisation du m\u00e9tabolisme calcique, les donn\u00e9es \u00e0 deux ans de l\u2019\u00e9tude PaTHway, r\u00e9cemment publi\u00e9es, mettent en avant un param\u00e8tre particuli\u00e8rement important pour le pronostic \u00e0 long terme : la fonction r\u00e9nale. <\/strong><\/p>\n\n

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L’hypoparathyro\u00efdie chronique fait partie des rares maladies endocriniennes pour lesquelles aucun traitement hormonal substitutif ciblant la cause n’\u00e9tait disponible depuis des d\u00e9cennies. Ce n’\u00e9tait pas le d\u00e9ficit hormonal sous-jacent qui……... <\/p>\n

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