{"id":565968,"date":"2026-09-10T02:00:00","date_gmt":"2026-09-10T00:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/quels-sont-les-principaux-facteurs-de-changement\/"},"modified":"2026-09-21T10:59:27","modified_gmt":"2026-09-21T08:59:27","slug":"quels-sont-les-principaux-facteurs-de-changement","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/fr\/quels-sont-les-principaux-facteurs-de-changement\/","title":{"rendered":"Quels sont les principaux facteurs de changement ?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>La n\u00e9phropathie \u00e0 IgA, \u00e9galement appel\u00e9e \u00ab maladie de Berger \u00bb, est la forme la plus courante de glom\u00e9rulon\u00e9phrite au monde. Il s\u2019agit d\u2019une maladie r\u00e9nale \u00e0 m\u00e9diation immunitaire dont le diagnostic repose sur l\u2019analyse des urines et une biopsie r\u00e9nale. Les progr\u00e8s r\u00e9alis\u00e9s dans la recherche sur les m\u00e9canismes physiopathologiques ont conduit \u00e0 la mise au point de strat\u00e9gies th\u00e9rapeutiques innovantes, pour lesquelles il existe d\u00e9sormais des donn\u00e9es issues de plusieurs essais de phase III\u2013 parmi lesquelles figurent, outre les prot\u00e9ines de fusion ciblant les cytokines BAFF et\/ou APRIL, des antagonistes s\u00e9lectifs des r\u00e9cepteurs de l\u2019endoth\u00e9line A et des inhibiteurs du compl\u00e9ment. Par ailleurs, il existe \u00e9galement des nouvelles int\u00e9ressantes concernant des options th\u00e9rapeutiques qui ont \u00e9galement franchi les \u00e9tapes d\u2019autorisation en Europe pour l\u2019IgAN.  <\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/fr\/mon-compte\/paquets\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/fr\/se-connecter\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Ffr%2Fquels-sont-les-principaux-facteurs-de-changement%2F\">Connectez-vous ici<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>La n\u00e9phropathie \u00e0 IgA, \u00e9galement appel\u00e9e \u00ab maladie de Berger \u00bb, est la forme la plus courante de glom\u00e9rulon\u00e9phrite au monde. Il s\u2019agit d\u2019une maladie r\u00e9nale \u00e0 m\u00e9diation immunitaire dont&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/fr\/mon-compte\/paquets\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/fr\/se-connecter\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Ffr%2Fquels-sont-les-principaux-facteurs-de-changement%2F\">Connectez-vous ici<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":565972,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"N\u00e9phropathie \u00e0 IgA : un paysage th\u00e9rapeutique en pleine \u00e9volution  ","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11549,11527,11315,11434,11535],"tags":[101119,101096,48481,101116,101117,48483,101115,54417,101102,27728,54431,99512,101090,101093,101111,101099,101103,101106,77607,61160,101109,101098,99522,101092,101107,84427,101118,101113],"powerkit_post_featured":[],"class_list":["post-565968","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-fr","category-etudes","category-medecine-interne-generale","category-nephrologie-fr","category-rapports-de-congres","tag-align","tag-antagonistes-selectifs-des-recepteurs-de-lendotheline-a","tag-april-fr","tag-atacicept","tag-atrasentan","tag-baff-fr","tag-bion-1301","tag-biopsie-renale","tag-budesonide-par-voie-orale","tag-cytokines","tag-glomerulonephrite","tag-inhibiteurs-du-complement","tag-maladie-de-berger","tag-maladie-renale-a-mediation-immunitaire","tag-moustache-de-fumeur-de-cigarette","tag-nefigan","tag-nefigard","tag-nefxtend","tag-nephropathie-a-iga","tag-origin-fr","tag-protect","tag-proteines-de-fusion","tag-ravulizumab","tag-resultats-de-lanalyse-durine","tag-sibeprenlimab","tag-sparsentan-fr","tag-telitacicept","tag-visionnaire","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-14 21:10:16","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"fr_FR","wpml_translations":{"it_IT":{"locale":"it_IT","id":565940,"slug":"quali-sono-i-principali-fattori-di-cambiamento","post_title":"Quali sono i principali fattori di cambiamento?","href":"https:\/\/medizinonline.com\/it\/quali-sono-i-principali-fattori-di-cambiamento\/"},"pt_PT":{"locale":"pt_PT","id":565952,"slug":"quais-sao-os-principais-fatores-de-mudanca","post_title":"Quais s\u00e3o os principais fatores de mudan\u00e7a?","href":"https:\/\/medizinonline.com\/pt-pt\/quais-sao-os-principais-fatores-de-mudanca\/"},"es_ES":{"locale":"es_ES","id":565963,"slug":"cuales-son-los-factores-mas-importantes-que-marcan-un-punto-de-inflexion","post_title":"\u00bfCu\u00e1les son los factores m\u00e1s importantes que marcan un punto de inflexi\u00f3n?","href":"https:\/\/medizinonline.com\/es\/cuales-son-los-factores-mas-importantes-que-marcan-un-punto-de-inflexion\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/565968","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/comments?post=565968"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/565968\/revisions"}],"predecessor-version":[{"id":566955,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/posts\/565968\/revisions\/566955"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media\/565972"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/media?parent=565968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/category?post=565968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/tags?post=565968"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/fr\/wp-json\/wp\/v2\/powerkit_post_featured?post=565968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}