{"id":566577,"date":"2026-09-09T22:00:00","date_gmt":"2026-09-09T20:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/approcci-terapeutici-basati-sulle-parp-molecolari-e-immunologici\/"},"modified":"2026-09-21T10:59:34","modified_gmt":"2026-09-21T08:59:34","slug":"approcci-terapeutici-basati-sulle-parp-molecolari-e-immunologici","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/it\/approcci-terapeutici-basati-sulle-parp-molecolari-e-immunologici\/","title":{"rendered":"Approcci terapeutici basati sulle PARP, molecolari e immunologici"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>In occasione dell\u2019ASCO 2026 sono stati presentati diversi approcci terapeutici per il carcinoma ovarico sieroso di alto grado (HGSOC). Tra questi figuravano dati aggiornati sulla caratterizzazione genomica dell\u2019HRD nell\u2019ambito della terapia di mantenimento con PARP e risultati relativi al trattamento neoadiuvante con il coniugato anticorpo-principio attivo mirato FR\u03b1Mirvetuximab soravtansine, un coniugato anticorpo-farmaco mirato contro FR\u03b1, in associazione con il carboplatino. Sono stati inoltre discussi approcci immunologici quali l\u2019inibizione dei checkpoint, le strategie vaccinali e le terapie cellulari adottive.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/it\/il-mio-conto\/pacchetti\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/it\/effettuare-il-login\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fit%2Fapprocci-terapeutici-basati-sulle-parp-molecolari-e-immunologici%2F\">Accedi<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>In occasione dell\u2019ASCO 2026 sono stati presentati diversi approcci terapeutici per il carcinoma ovarico sieroso di alto grado (HGSOC). Tra questi figuravano dati aggiornati sulla caratterizzazione genomica dell\u2019HRD nell\u2019ambito della&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/it\/il-mio-conto\/pacchetti\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/it\/effettuare-il-login\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fit%2Fapprocci-terapeutici-basati-sulle-parp-molecolari-e-immunologici%2F\">Accedi<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":566581,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"HGSOC","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11550,11409,11376,11522,11515],"tags":[102071,58005,102073,101604,102080,102074,102072,13611,14707,19473,102078,102077,102076,102070,102075],"powerkit_post_featured":[],"class_list":["post-566577","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-it","category-ginecologia-it","category-oncologia-it","category-rapporti-del-congresso","category-studi","tag-brca1-2","tag-carboplatino","tag-carcinoma-ovarico-sieroso-di-alto-grado","tag-congresso-annuale-dellasco-2026","tag-coniugati-anticorpo-principio-attivo-adc","tag-deficit-di-ricombinazione-omologa-hrd","tag-hgsoc","tag-immunoterapia","tag-inibitori-del-checkpoint","tag-inibitori-parp","tag-mirvetuximab-soravtansine","tag-recettore-alfa-del-folato-fr","tag-terapia-di-mantenimento-con-parp","tag-terapia-neoadiuvante-2","tag-wgs-hrd","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-16 00:42:49","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"it_IT","wpml_translations":{"pt_PT":{"locale":"pt_PT","id":566585,"slug":"abordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas","post_title":"Abordagens terap\u00eauticas baseadas na PARP, moleculares e imunol\u00f3gicas","href":"https:\/\/medizinonline.com\/pt-pt\/abordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas\/"},"es_ES":{"locale":"es_ES","id":566602,"slug":"enfoques-terapeuticos-basados-en-parp-moleculares-e-inmunologicos","post_title":"Enfoques terap\u00e9uticos basados en PARP, moleculares e inmunol\u00f3gicos","href":"https:\/\/medizinonline.com\/es\/enfoques-terapeuticos-basados-en-parp-moleculares-e-inmunologicos\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/posts\/566577","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/comments?post=566577"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/posts\/566577\/revisions"}],"predecessor-version":[{"id":566960,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/posts\/566577\/revisions\/566960"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/media\/566581"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/media?parent=566577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/category?post=566577"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/tags?post=566577"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/it\/wp-json\/wp\/v2\/powerkit_post_featured?post=566577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}