{"id":566585,"date":"2026-09-09T22:00:00","date_gmt":"2026-09-09T20:00:00","guid":{"rendered":"https:\/\/medizinonline.com\/abordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas\/"},"modified":"2026-09-21T10:59:35","modified_gmt":"2026-09-21T08:59:35","slug":"abordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/pt-pt\/abordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas\/","title":{"rendered":"Abordagens terap\u00eauticas baseadas na PARP, moleculares e imunol\u00f3gicas"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Na ASCO 2026 foram apresentadas diversas abordagens terap\u00eauticas para o cancro do ov\u00e1rio seroso de alto grau (HGSOC). Estas inclu\u00edram dados recentes sobre a caracteriza\u00e7\u00e3o gen\u00f3mica da HRD no contexto da terapia de manuten\u00e7\u00e3o com PARP, bem como conclus\u00f5es sobre o tratamento neoadjuvante com o conjugado FR\u03b1, o conjugado anticorpo-f\u00e1rmaco direcionado para FR\u03b1, Mirvetuximab soravtansine, associado \u00e0 carboplatina. S\u00e3o igualmente discutidas abordagens imunol\u00f3gicas, tais como a inibi\u00e7\u00e3o de pontos de controlo, estrat\u00e9gias de vacina\u00e7\u00e3o e terapias celulares adotivas.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Fabordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Na ASCO 2026 foram apresentadas diversas abordagens terap\u00eauticas para o cancro do ov\u00e1rio seroso de alto grau (HGSOC). Estas inclu\u00edram dados recentes sobre a caracteriza\u00e7\u00e3o gen\u00f3mica da HRD no contexto&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Fabordagens-terapeuticas-baseadas-na-parp-moleculares-e-imunologicas%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":566586,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"HGSOC","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11551,11521,11419,11379,11529],"tags":[102093,58071,102098,101624,102109,102099,102095,13523,14722,19482,102107,102106,102103,102091,102101],"powerkit_post_featured":[],"class_list":["post-566585","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-pt","category-estudos","category-ginecologia-pt-pt","category-oncologia-pt-pt","category-relatorios-do-congresso","tag-brca1-2","tag-carboplatina","tag-carcinoma-ovariano-seroso-de-alto-grau","tag-congresso-anual-da-asco-de-2026","tag-conjugados-de-anticorpos-e-principios-ativos-adc","tag-deficiencia-de-recombinacao-homologa-hrd","tag-hgsoc","tag-imunoterapia","tag-inibidores-de-pontos-de-verificacao","tag-inibidores-parp","tag-mirvetuximab-soravtansine","tag-receptor-de-folato-alfa-fr","tag-terapia-de-manutencao-da-parp","tag-terapia-neoadjuvante-2","tag-wgs-hrd","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-16 00:47:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"pt_PT","wpml_translations":{"es_ES":{"locale":"es_ES","id":566602,"slug":"enfoques-terapeuticos-basados-en-parp-moleculares-e-inmunologicos","post_title":"Enfoques terap\u00e9uticos basados en PARP, moleculares e inmunol\u00f3gicos","href":"https:\/\/medizinonline.com\/es\/enfoques-terapeuticos-basados-en-parp-moleculares-e-inmunologicos\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/566585","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/comments?post=566585"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/566585\/revisions"}],"predecessor-version":[{"id":566961,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/566585\/revisions\/566961"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media\/566586"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media?parent=566585"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/category?post=566585"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/tags?post=566585"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/powerkit_post_featured?post=566585"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}