{"id":567052,"date":"2026-10-09T12:30:00","date_gmt":"2026-10-09T10:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=567052"},"modified":"2026-09-21T11:25:38","modified_gmt":"2026-09-21T09:25:38","slug":"sglt2i-metformina-ou-ambos","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/pt-pt\/sglt2i-metformina-ou-ambos\/","title":{"rendered":"SGLT2i, metformina ou ambos?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>A metformina continua a ser o tratamento farmacol\u00f3gico de primeira linha no diabetes tipo 2 rec\u00e9m-diagnosticado, enquanto os inibidores do cotransportador de s\u00f3dio-glicose 2(SGLT2) s\u00e3o indicados na presen\u00e7a de doen\u00e7a cardiovascular ou renal estabelecida ou de um risco cardiovascular elevado. Foi investigado se o tratamento com um inibidor de SGLT2 numa fase precoce altera a fun\u00e7\u00e3o e a estrutura vasculares em indiv\u00edduos sem tratamento pr\u00e9vio com diabetes tipo 2 rec\u00e9m-diagnosticada, atrav\u00e9s da compara\u00e7\u00e3o entre a dapagliflozina em monoterapia, a metformina em monoterapia e a sua combina\u00e7\u00e3o.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Fsglt2i-metformina-ou-ambos%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>A metformina continua a ser o tratamento farmacol\u00f3gico de primeira linha no diabetes tipo 2 rec\u00e9m-diagnosticado, enquanto os inibidores do cotransportador de s\u00f3dio-glicose 2(SGLT2) s\u00e3o indicados na presen\u00e7a de doen\u00e7a&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Fsglt2i-metformina-ou-ambos%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":567056,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Terapia de primeira linha na DM2","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11551,11397,11521,11524],"tags":[23326,12023,102218,33459,11680,19498,86759,80022,11955],"powerkit_post_featured":[],"class_list":["post-567052","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-pt","category-endocrinologia-e-diabetologia-2","category-estudos","category-formacao-continua","tag-dapagliflozin-pt-pt","tag-diabetes-tipo-2-pt-pt","tag-espessura-da-camada-intima-media-da-carotida","tag-inibidores-sglt2-pt-pt","tag-metformin-pt-pt","tag-risco-cardiovascular","tag-sglt2i","tag-t2d-pt-pt","tag-terapia-de-primeira-linha","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-16 14:39:51","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"pt_PT","wpml_translations":{"es_ES":{"locale":"es_ES","id":567060,"slug":"sglt2i-metformina-o-ambas","post_title":"\u00bfSGLT2i, metformina o ambas?","href":"https:\/\/medizinonline.com\/es\/sglt2i-metformina-o-ambas\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567052","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/comments?post=567052"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567052\/revisions"}],"predecessor-version":[{"id":568102,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567052\/revisions\/568102"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media\/567056"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media?parent=567052"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/category?post=567052"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/tags?post=567052"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/powerkit_post_featured?post=567052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}