{"id":567176,"date":"2026-10-12T12:30:00","date_gmt":"2026-10-12T10:30:00","guid":{"rendered":"https:\/\/medizinonline.com\/?p=567176"},"modified":"2026-09-21T11:25:34","modified_gmt":"2026-09-21T09:25:34","slug":"alteracao-precoce-da-contrarregulacao-do-glucagon","status":"publish","type":"post","link":"https:\/\/medizinonline.com\/pt-pt\/alteracao-precoce-da-contrarregulacao-do-glucagon\/","title":{"rendered":"Altera\u00e7\u00e3o precoce da contrarregula\u00e7\u00e3o do glucagon"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Uma regula\u00e7\u00e3o contr\u00e1ria mediada pelo glucagon perturbada constitui um fator essencial para a ocorr\u00eancia de hipoglicemias graves na diabetes tipo 1 (DT1). Embora este fen\u00f3meno esteja bem descrito em adultos, o seu in\u00edcio e evolu\u00e7\u00e3o em crian\u00e7as e adolescentes continuam a ser insuficientemente caracterizados, uma vez que os dados a longo prazo relativos \u00e0 DT1 pedi\u00e1trica s\u00e3o limitados. Os indicadores derivados da monitoriza\u00e7\u00e3o cont\u00ednua da glicemia (CGM) foram agora identificados como marcadores substitutos n\u00e3o invasivos de uma contrarregula\u00e7\u00e3o comprometida, os quais poder\u00e3o servir para uma estratifica\u00e7\u00e3o precoce do risco de hipoglicemias em crian\u00e7as com DT1.<\/strong><\/p>\n\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Falteracao-precoce-da-contrarregulacao-do-glucagon%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Uma regula\u00e7\u00e3o contr\u00e1ria mediada pelo glucagon perturbada constitui um fator essencial para a ocorr\u00eancia de hipoglicemias graves na diabetes tipo 1 (DT1). Embora este fen\u00f3meno esteja bem descrito em adultos,&#8230;&hellip;... <\/p>\n<div class=\"pmpro\"><div class=\"pmpro_card pmpro_content_message\"><div class=\"pmpro_card_content\">Dieser Inhalt ist nur f\u00fcr Benutzer der Gruppe: Medizinische Fachperson zug\u00e4nglich <br \/><a href=\"https:\/\/medizinonline.com\/pt-pt\/a-minha-conta\/pacotes\/\">Jetzt beitreten<\/a><\/div><div class=\"pmpro_card_actions pmpro_font-medium\">Already a member? <a href=\"https:\/\/medizinonline.com\/pt-pt\/iniciar-sessao\/?redirect_to=https%3A%2F%2Fmedizinonline.com%2Fpt-pt%2Falteracao-precoce-da-contrarregulacao-do-glucagon%2F\">Log in here<\/a><\/div><\/div><\/div>","protected":false},"author":7,"featured_media":567178,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","cat_1_feature_home_top":false,"cat_2_editor_pick":false,"csco_eyebrow_text":"Diabetes tipo 1 na inf\u00e2ncia  ","footnotes":"","_members_access_role":[],"_members_access_error":""},"category":[11551,11397,11521,11524,11450],"tags":[70342,102302,11677,79997,74292,40059,61382,15833],"powerkit_post_featured":[],"class_list":["post-567176","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rx-pt","category-endocrinologia-e-diabetologia-2","category-estudos","category-formacao-continua","category-pediatria-pt-pt","tag-cgm-pt-pt-2","tag-contrarregulacao-mediada-pelo-glucagon","tag-diabetes-pt-pt","tag-diabetes-tipo-1-pt-pt","tag-dm1","tag-glucagon-pt-pt","tag-hipoglicemias","tag-pediatria-pt-pt","pmpro-level-required","pmpro-level-1","pmpro-no-access"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-20 01:09:23","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"wpml_current_locale":"pt_PT","wpml_translations":{"es_ES":{"locale":"es_ES","id":567188,"slug":"alteracion-precoz-de-la-contrarregulacion-del-glucagon","post_title":"Alteraci\u00f3n precoz de la contrarregulaci\u00f3n del glucag\u00f3n","href":"https:\/\/medizinonline.com\/es\/alteracion-precoz-de-la-contrarregulacion-del-glucagon\/"}},"_links":{"self":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567176","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/comments?post=567176"}],"version-history":[{"count":1,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567176\/revisions"}],"predecessor-version":[{"id":568098,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/posts\/567176\/revisions\/568098"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media\/567178"}],"wp:attachment":[{"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/media?parent=567176"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/category?post=567176"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/tags?post=567176"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/medizinonline.com\/pt-pt\/wp-json\/wp\/v2\/powerkit_post_featured?post=567176"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}