This content is machine translated Research Protein 2, which contains the LEM domain, is essential for heart development The integrity of the nuclear envelope is essential for the compartmentalization of the nucleus and the cytoplasm. Importantly, mutations in genes coding for the nuclear envelope and related proteins are…
View Post 5 min This content is machine translated Hypertrophic obstructive cardiomyopathy Targeted drug treatment possible Hypertrophic cardiomyopathies are characterized by a thickening of the heart muscle without accompanying dilatation. In 70% of cases, there is an obstruction of the left ventricular outflow tract, which is…
View Post 8 min This content is machine translated Casuistry Dyspnea in the outpatient setting – also consider rare causes Prof. Dr. med. Thurnheer, Cantonal Hospital Münsterlingen, impressively demonstrated that it is not always necessary to be satisfied with the working diagnosis of “dyspnoea of unclear aetiology”, but that detailed…
View Post 14 min This content is machine translated Heart failure Interventional treatment of the tricuspid valve Long considered the “forgotten valve,” the tricuspid valve (TC) has gained increasing attention and recognition in recent years. This is due in no small part to the development of new… CME-Test
View Post 20 min This content is machine translated Lipoprotein(a) Current and future treatment options Twenty percent of the population have elevated Lp(a) concentrations, which are associated with an increased risk of cardiovascular disease. There is currently no FDA or EMA approved pharmacologic therapy to… CME-Test
View Post 4 min This content is machine translated Rare diseases: hATTR amyloidosis What treatment options are available today? Transthyretin-associated amyloidosis (ATTR) is hereditary (hATTR) or acquired (wATTR). In patients with unclear left ventricular hypertrophy and characteristic findings, it is recommended to investigate the presence of cardiac amyloidosis. In…
View Post 4 min This content is machine translated Acute myocardial infarction and heart failure in young diabetics Type 2 with a poor risk profile for CVD Type 1 and type 2 diabetes differ in many ways, but both types are strongly associated with a high risk of cardiovascular complications. T2D at a young age is considered…
View Post 2 min This content is machine translated "smarter medicine – Choosing Wisely Switzerland" Top 5 list for the field of angiology The Swiss Society of Angiology advises against long-term use of aspirin in patients with no evidence of cardiovascular disease. This makes a clear statement on this controversial topic. The remaining…
View Post 5 min This content is machine translated Heart failure and type 2 diabetes SGLT-2-i now recommended for the entire LVEF spectrum Based on data from large clinical trials, it is currently recommended that all patients with diabetes and chronic heart failure – regardless of left ventricular ejection fraction – are treated…
View Post 4 min This content is machine translated SGLT2i for heart failure HF prevalence in diabetes patients is underestimated in everyday clinical practice SGLT2 inhibitors can significantly reduce the risk of hospitalization for heart failure (HF) and death from cardiovascular causes in patients with diabetes and HF. However, the diagnosis of HF is…
View Post 4 min This content is machine translated Type 2 diabetes ESC recommendations for reducing cardiovascular risk Patients with type 2 diabetes have a greatly increased risk of developing cardiovascular disease compared to healthy people in the same age group. The current guidelines published in the European…
