This content is machine translated Juvenile Idiopathic Arthritis Early Detection and Targeted Treatment in an Interdisciplinary Setting Juvenile idiopathic arthritis is the most common autoimmune disease in childhood—the incidence among children under 16 is approximately 1 in 1,000. Early diagnosis and appropriate treatment remain a challenge. As...…
View Post 6 min This content is machine translated Disorders of the Gut-Brain Interaction Rome V Criteria: What Has Changed, and What Has Remained the Same? Disorders of the gut-brain interaction (DGBI) are characterized by gastrointestinal symptoms resulting from a combination of various factors—including motility disorders, visceral hypersensitivity, and dysbiosis. For many years, research into and...…
View Post 5 min This content is machine translated Tourette Syndrome What can be done to treat this tic disorder? Gilles de la Tourette syndrome (or “Tourette syndrome” for short) is a neurodevelopmental disorder characterized by motor and vocal tics and often accompanied by attention deficits, hyperactivity, and obsessive-compulsive disorder....…
View Post 4 min This content is machine translated Chronic Hepatitis B: Is a Cure in Sight? Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
View Post 9 min This content is machine translated Congenital Vascular Malformations Personalized Treatment Before a Planned Pregnancy Vascular malformations have a prevalence of 1% and an incidence of 3–5 per 10,000. Anomalies can affect any organ system in children and adults. Mosaic mutations occurring during embryonic development...… CME-Test
View Post 14 min This content is machine translated Fibromyalgia Syndrome Development, Diagnosis, Epidemiology, and Treatment of a Disease Entity According to the 2010 and 2011 ACR diagnostic criteria, as revised in 2016, fibromyalgia syndrome is a multisymptomatic disorder whose primary symptom is chronic tendon-muscle pain that shifts and spreads...… CME-Test
View Post 5 min This content is machine translated Clinically Suspected Arthralgias “Watchful waiting” or intervention? The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
View Post 6 min This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena? From Risk Stratification to Post-Endoscopic Management Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
View Post 15 min This content is machine translated Obesity, Nutrition, and Mental Health Depression, Binge Eating, Internalized Stigma Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
View Post 5 min This content is machine translated From Hypertension to Heart Failure? When and how to intervene High blood pressure and hypertensive heart disease are the most significant risk factors for heart failure. The symptoms are very nonspecific, especially in the early stages of heart failure. Measuring...…
View Post 10 min This content is machine translated Switzerland's First PTH Replacement Therapy Palopegteriparatide for Chronic Hypoparathyroidism Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
