This content is machine translated Autoimmune Liver Diseases Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New? PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 13 min This content is machine translated Obesity Treatment Oral GLP-1 Therapies: ATTAIN-1 and OASIS-4—The Next Leap Forward Injectable GLP-1 receptor agonists and the dual GIP/GLP-1 agonist tirzepatide have redefined pharmacological obesity treatment and achieved weight loss in the range of 15 to 20% in clinical trials. Nevertheless,...…
View Post 4 min This content is machine translated Disorders of the Gut-Brain Interaction Peppermint-Caraway Oil Supplement Proves Effective in Phase IV Trial In primary care , disorders of the gut-brain axis—also known as functional gastrointestinal disorders—are very common. Herbal remedies, such as a proprietary combination of peppermint oil (Mentha × piperita L.)...…
View Post 5 min This content is machine translated Gepante for Migraines Relief from pain, symptoms, and improved functional ability—both acute and preventive Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
View Post 12 min This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance Potassium binders as enablers of RAASi optimization Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
View Post 3 min This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy Remodeling can be counteracted through a proactive treatment strategy If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
View Post 3 min This content is machine translated From symptom to diagnosis Gynecomastia and Adipomastia The term ” gynecomastia ” refers to the enlargement of the mammary gland in men, which may be unilateral or bilateral. True gynecomastia, caused by an increase in glandular tissue,...…
View Post 7 min This content is machine translated Plastic surgery and reconstructive microsurgery for DFS Functional limb preservation between infection control, vascular medicine and resurfacing Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood...… CME-Test
View Post 12 min This content is machine translated SURPASS-CVOT Tirzepatide versus Dulaglutide in T2D with ASCVD GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
View Post 6 min This content is machine translated Secondary prevention after ACS: individually optimized lipid management Trend towards early combination therapy and new strategies for lowering Lp(a) Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
