This content is machine translated Sjögren's Syndrome in Early Childhood Children often develop lymphomas To date, there has been limited knowledge regarding the clinical features of pediatric Sjögren’s syndrome and its impact on quality of life. Because it is rare, it is often diagnosed...…
View Post 7 min This content is machine translated Osgood-Schlatter Disease Clinical Presentation, Diagnosis, and Treatment Typical symptoms of this osteochondrosis and inflammation of the tibial tuberosity include stress-related symptoms in young athletes. Children between the ages of 10 and 15 are most commonly affected. Symptoms...…
View Post 7 min This content is machine translated Type 1 Diabetes: A New Disease-Modifying Treatment Approach Slowing the loss of β-cell function and delaying the progression of the disease Type 1 diabetes is the most common metabolic disorder among children and adolescents. The clinical manifestation of type 1 diabetes is preceded by presymptomatic islet cell autoimmunity, which can be...…
View Post 7 min This content is machine translated Juvenile Idiopathic Arthritis Early Detection and Targeted Treatment in an Interdisciplinary Setting Juvenile idiopathic arthritis is the most common autoimmune disease in childhood—the incidence among children under 16 is approximately 1 in 1,000. Early diagnosis and appropriate treatment remain a challenge. As...…
View Post 5 min This content is machine translated Case study Orofacial Manifestations of Phelan-McDermid Syndrome Phelan-McDermid syndrome is a rare genetic disorder primarily caused by deletions or structural changes in chromosome 22q13. In a publication from 2025, De Falco et al. described the first documented...…
View Post 4 min This content is machine translated Epidermolysis bullosa Promoting Wound Healing with Gene Therapies and Birch Bark Extract Epidermolysis bullosa (EB) requires an interdisciplinary management approach tailored to the diagnosed EB subtype. Recently, new therapeutic approaches have been approved to improve symptomatic treatment. While a gel formulation containing...…
View Post 7 min This content is machine translated Pediatric Retinoblastoma The Tumor Microenvironment and Modern Eye-Sparing Therapies Retinoblastoma is considered the prototypical pediatric tumor, whose biology is closely linked to the development of immature retinal tissue. New molecular and immunological findings show that the tumor microenvironment is...…
View Post 27 min This content is machine translated Pediatric Brain Tumors Psychiatry versus Neuro-Oncology: Diagnostic Pitfalls Pediatric brain tumors often begin with nonspecific symptoms—some physical, some behavioral—that can be attributed to internal medicine or psychiatric differential diagnoses, thereby presenting typical diagnostic pitfalls. Clinical case examples from...… CME-Test
View Post 4 min This content is machine translated Bronchiolitis obliterans Out of shape even without popcorn Post-infectious bronchiolitis obliterans (PIBO) develops in childhood and is characterized by irreversible airway obstruction and persistent impairment of lung function. Although it is known that exercise capacity may be impaired,...…
View Post 7 min This content is machine translated Obesity in Children and Adolescents Gene-Environment Interactions: Polygenic or Monogenic Determinants? In the context of precision medicine, a differentiated approach to the diagnosis of obesity provides an essential foundation for implementing improved strategies for prevention, treatment, and prognosis. Obesity is often...…
View Post 5 min This content is machine translated Viloxazine for ADHD A non-stimulating option—but with limited evidence ADHD affects about 5–7% of children and adolescents and 2–5% of adults. Although it is generally considered a childhood disorder, symptoms persist into adulthood for the majority of those affected....…
