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Endocrinology and Diabetology

589 posts
  • This content is machine translated Type 1 Diabetes: A New Disease-Modifying Treatment Approach

Slowing the loss of β-cell function and delaying the progression of the disease

Type 1 diabetes is the most common metabolic disorder among children and adolescents. The clinical manifestation of type 1 diabetes is preceded by presymptomatic islet cell autoimmunity, which can be...…
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  • 15 min
  • This content is machine translated Obesity, Nutrition, and Mental Health

Depression, Binge Eating, Internalized Stigma

Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
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  • 10 min
  • This content is machine translated Switzerland's First PTH Replacement Therapy

Palopegteriparatide for Chronic Hypoparathyroidism

Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
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  • 3 min
  • This content is machine translated Atherosclerotic Coronary Plaques in High-Risk Patients

Who benefits from preventive PCI?

For patients with ASCVD, modern imaging techniques such as CCTA and cardiac MRI often provide a solid basis for subsequent treatment decisions. The invasive cardiac catheterization procedure is currently used...…
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  • 5 min
  • This content is machine translated Colorectal Cancer

Insulin Resistance, Obesity, and Progression

Colorectal cancer is one of the most common malignant tumors worldwide and is increasingly linked to metabolic disorders such as insulin resistance and obesity. New epidemiological data show significant shifts...…
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  • 12 min
  • This content is machine translated Hepatology and Metabolism

The Mediterranean Diet for MASLD/MASH—What the EASL-EASD-EASO Guidelines Specifically Recommend

Since an international Delphi consensus in 2023, the condition formerly known as nonalcoholic fatty liver disease (NAFLD) has been called MASLD— “metabolic dysfunction-associated steatotic liver disease.” It is defined as...…
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  • 18 min
  • This content is machine translated From an antidiabetic drug to a distinct class of cardiorenal therapies

The Incretin Revolution in Cardiology

Within a decade, incretin mimetics have evolved from blood-sugar-lowering diabetes medications into one of the most dynamic classes of drugs in cardiovascular medicine. GLP-1 receptor agonists (GLP-1-RA) have been shown...…
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  • 12 min
  • This content is machine translated Cardiology and Nutrition

Ultra-Processed Foods and Cardiovascular Risk—The New AHA Position

Ultra-processed foods (UPFs ) account for a significant portion of energy intake in Western countries—in the United States, an estimated more than half. Given this ubiquity and a growing number...…
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  • 7 min
  • This content is machine translated Obesity: A Multimodal and Interdisciplinary Approach

New Swiss Clinical Practice Guideline Provides Guidance

The guidelines developed by Swiss professional associations (Swiss Obesity Clinical Practice Guidance) contain evidence-based recommendations for the diagnosis and treatment of obesity, with a focus on improving health, quality of...…
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  • 6 min
  • This content is machine translated Advanced Thyroid Cancer

Molecular Mechanisms and New Therapeutic Approaches

Thyroid carcinomas exhibit remarkable biological heterogeneity, which is increasingly shaping modern diagnosis and treatment. Molecular markers and innovative treatment approaches are fundamentally changing our understanding of pathogenesis, prognosis, and clinical...…
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  • 18 min
  • This content is machine translated From Risk Identification to Anti-Inflammatory Intervention

Inflammation as a Treatment Goal in Its Own Right

For decades, cardiovascular prevention was essentially a story about cholesterol. Yet a significant proportion of patients experience adverse events despite optimally controlled lipid levels—a reflection of a residual risk that...…
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